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Prlr

PRLR,即催乳素受体,是一种主要在垂体前叶以外的多种组织中表达的跨膜蛋白。催乳素受体通过与催乳素(PRL)结合,启动细胞内的信号传导过程,主要通过JAK2-STAT信号通路发挥作用,导致细胞核内特定基因的转录激活,从而影响细胞增殖、分化和功能。PRLR的信号转导还涉及MAPK和PI3K/AKT等其他信号通路,这些通路在调节免疫反应、细胞生长和代谢等方面发挥作用。催乳素受体的生物学意义广泛,它不仅在乳腺发育和泌乳中发挥关键作用,还参与调节生殖系统、免疫系统和神经系统的功能。PRLR的功能异常与多种疾病有关,包括某些类型的癌症和生殖功能障碍。

热销产品

Recombinant Human Prolactin receptor (PRLR), partial (Active) (CSB-MP018727HU1d7)

验证数据

CSB-MP018727HU1d7

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP018727HU1d7

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human PRLR at 2 μg/ml can bind Anti-PRLR recombinant antibody (CSB-RA018727A0HU), the EC50 is 126.8-171.9 ng/mL.

PRLR Recombinant Monoclonal Antibody (CSB-RA018727A0HU)

验证数据

CSB-RA018727A0HU

The Binding Activity of Human PRLR with Anti-PRLR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PRLR (CSB-MP018727HU1d7) at 2 μg/mL can bind Anti-PRLR recombinant antibody, the EC50 is 126.8-171.9 ng/mL.

CSB-RA018727A0HU

The Binding Activity of Mouse Prlr with Anti-PRLR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Prlr at 5 μg/mL (CSB-MP018727MO) can bind Anti-PRLR recombinant antibody, the EC50 is 4.021-8.706 ng/mL.

Prlr Antibodies

Prlr for Homo sapiens (Human)

Prlr Proteins

Prlr Proteins for Oryctolagus cuniculus (Rabbit)

Prlr Proteins for Homo sapiens (Human)

Prlr Proteins for Ovis aries (Sheep)

Prlr Proteins for Rattus norvegicus (Rat)

Prlr Proteins for Sus scrofa (Pig)

Prlr Proteins for Meleagris gallopavo (Common turkey)

Prlr Proteins for Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)

Prlr Proteins for Columba livia (Domestic pigeon)

Prlr Proteins for Mus musculus (Mouse)

Prlr Proteins for Bos taurus (Bovine)

Prlr Proteins for Cervus elaphus (Red deer)