Csf1r

CSF1R，即集落刺激因子1受体，别名CD115、MCSFR、Oncogen FMS、Proto-oncogene c-Fms、V-FMS McDonough feline sarcoma viral oncogen homolog、formerly。它是一种由CSF1R基因编码的跨膜受体，属于酪氨酸激酶受体家族成员。CSF1R在多种组织中表达，尤其在单核-巨噬细胞系中表达量较高。CSF1R的作用机制主要涉及与集落刺激因子1（CSF-1）和白细胞介素34（IL-34）等配体结合，激活受体的酪氨酸激酶活性，进而引发细胞内信号传导。配体结合导致受体二聚化和自磷酸化，激活下游的多个信号通路，包括PI3K/Akt、MAPK、STAT等。CSF1R参与调节单核细胞、巨噬细胞、破骨细胞的增殖、分化和存活。CSF1R信号通路的激活对于维持免疫系统和骨骼系统的正常功能至关重要。此外，CSF1R的功能异常与多种疾病有关，包括某些类型的癌症、免疫性疾病和炎症性疾病。因此，CSF1R是药物开发和疾病治疗中的一个潜在靶点。

热销产品

Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial (CSB-MP006044HUi10)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSF1R Antibody (CSB-PA001597)

验证数据

Western Blot analysis of HT29 cells using c-Fms Polyclonal Antibody

Csf1r Antibody

Csf1r Protein

Csf1r ELISA Kit

Csf1r Antibodies

Csf1r for Felis silvestris catus

产品货号	产品名称	种属反应性	应用类型
CSB-PA006044LA01CA	CSF1R Antibody	Felis silvestris catus	ELISA

Csf1r for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA084386	Phospho-CSF1R (Tyr809) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA924224	Phospho-CSF1R (Tyr561) Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA202220	Phospho-CSF1R (Tyr708) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA696464	CSF1R (Ab-809) Antibody	Human,Mouse	ELISA,WB,IHC,IF
CSB-PA152912	Phospho-CSF1R (Tyr699) Antibody	Human	ELISA,WB
CSB-PA940519	Phospho-CSF1R (Tyr809) Antibody	Human	ELISA,IHC
CSB-PA001596	CSF1R Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA001597	CSF1R Antibody	Human	WB, IHC, IF, ELISA
CSB-PA007328	Phospho-CSF1R (Y809) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA007329	Phospho-CSF1R (Y699) Antibody	Human	WB, ELISA
CSB-PA007330	Phospho-CSF1R (Y708) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA007331	Phospho-CSF1R (Y723) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA007332	Phospho-CSF1R (Y561) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA007333	Phospho-CSF1R (Y809) Antibody	Human	IHC, ELISA
CSB-PA007334	CSF1R Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA007335	CSF1R Antibody	Human	WB, ELISA
CSB-PA007337	CSF1R Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA300271	CSF1R Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA678661	CSF1R Antibody	Human,Mouse,Rat	ELISA,WB

Csf1r Proteins

Csf1r Proteins for Felis catus (Cat) (Felis silvestris catus)

产品货号	产品名称	来源
CSB-YP006044CA CSB-BP006044CA CSB-MP006044CA CSB-EP006044CA-B	Recombinant Cat Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006044CA	Recombinant Cat Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	E.coli

Csf1r Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP006044HU CSB-EP006044HU CSB-BP006044HU CSB-EP006044HU-B	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-MP006044HU	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Mammalian cell
CSB-MP006044HUi10	Recombinant Human Macrophage colony-stimulating factor 1 receptor (CSF1R), partial	Mammalian cell

Csf1r Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP006044MO CSB-EP006044MO CSB-BP006044MO CSB-MP006044MO CSB-EP006044MO-B	Recombinant Mouse Macrophage colony-stimulating factor 1 receptor (Csf1r), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Csf1r Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

产品货号	产品名称	来源
CSB-YP888246DIL CSB-EP888246DIL CSB-BP888246DIL CSB-MP888246DIL CSB-EP888246DIL-B	Recombinant Danio rerio Macrophage colony-stimulating factor 1 receptor (csf1r), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli