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  4. Recombinant Uncharacterized protein F56D1.2 (F56D1.2)

Recombinant Uncharacterized protein F56D1.2 (F56D1.2)

  • 中文名称：
    秀丽隐杆线虫F56D1.2重组蛋白
  • 货号：
    CSB-CF608742CXY
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    F56D1.2
  • Uniprot No.：
  • 别名：
    ilcr-2; F56D1.2; Interleukin cytokine receptor-related protein 2; Interleukin-17 receptor-like protein 2
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    31-718
  • 氨基酸序列
    SVKSSAAASYTNASDYVLRNVFEHSDQCYKDSFVYVRADDKKSDPFITYSTTKECSERLK KNDLPEKLPTCPPGLIDLELKPVYVPKSQISYPYANLNISVTAHSSVDTIAFRLECLSAS DGSDVYCSNSKAMYINGVKEWPCRGIHLSSRVQYPTRFSYSCFRLTSFSVYAINATILPQ KCRVSTIMTAPYFDDMFPEILVDPTTNQSIITKTDPFWAPMLSADFSDKNAIWVRLGKAE RAECETMVVNVYKEHDDDSQKVTFLEILTVKCPETAVKWENQKAGRYLLTAYVPIRGCKF YCEKKERGCRQCLRTHLNLVIYKNRASLSWLALQKFKDYGFEIFIAVVVLLILIIVLAVT GFGYVLWRDKVRSREVRNIALTEFVKVMIVYADDNDLHTDCVKKLVENLRNCASCDPVFD LEKLITAEQIVPSRWLVDQISSLKKFIIVVSDCAEKILDTEASETHQLVQARPFADLFGP AMEMIIRDATHNFPEARKKYAVVRFNYSPHVPPNLAILNLPTFILPEQFAQLTAFLHNVE HTERANVTQNISEAQIHEWNLCASRMMSFFVRNPNWLETRWKPKDELAALHLKRQSPVIV PIQTEEDRIAASIKYNLVPPQALVDSDDEDDVDLQPHASHQNQPLILLPPEQCGPDSDSD SESDSSSESESESDNEGEDPKTIVVKKS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Forms a receptor complex together with receptor ilcr-1, which upon activation acts as a modulator of neuronal activity. Binding of the ligand ilc-17.1 to the ilcr-1/2 receptor complex triggers a signaling cascade that activates the downsteam signaling components actl-1, pik-1 and nfki-1, and results in increased neuronal activity in RMG interneurons in response to input from oxygen-sensing neurons. This leads to increased animal movement and promotes aggregation behavior.
  • 基因功能参考文献：
    1. EGL-15 and CLR-1 act in the hypodermis to regulate fluid homeostasis in worms PMID: 15115754
    2. Caenorhabditis elegans fibroblast growth factor receptor EGL-15 expression is required within epidermal cells and the substratum for most outgrowing axons, for appropriate outgrowth of specific axon classes to their target area. PMID: 15134634
    3. clr-1 encodes a transmembrane receptor protein tyrosine phosphatase (RPTP) that functions in AVM to inhibit signaling through the DCC family receptor UNC-40 and its effector, UNC-34/enabled PMID: 15232111
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed in most neurons, and in pharyngeal muscle.
  • 数据库链接：

    KEGG: cel:CELE_F56D1.2

    UniGene: Cel.17043