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Recombinant Sheep Aquaporin-1 (AQP1)

  • 中文名称：
    Recombinant Sheep Aquaporin-1(AQP1)
  • 货号：
    CSB-CF001957SH
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    AQP1
  • Uniprot No.：
  • 别名：
    AQP1; Aquaporin-1; AQP-1; Aquaporin-CHIP; Water channel protein for red blood cells and kidney proximal tubule
  • 种属：
    Ovis aries (Sheep)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-272
  • 氨基酸序列
    MASEFKKKLFWRAVVAEFLAMILFIFISIGSALGFHYPIKSNQTTGAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRAIMYIIAQCVGAIVATVILSGITSSLPDNSLGLNALAPGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRRDLGDSGPLAIGFSVALGHLLAIDYTGCGINPARSFGSSVITHNFQDHWIFWVGPFIGAALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
  • 基因功能参考文献：
    1. AQP1, 3, and 5 may constitute a transepithelial water pathway via glandular secretions and across the surface epithelium, which provides a possible means for rapid and controllable water movement in the nasal respiratory mucosa of a panting species PMID: 24956959
    2. The role of aquaporin 1 activated by cGMP in myocardial edema caused by cardiopulmonary bypass PMID: 24280641
    3. The obtained results indicated that in ENS of the ovine duodenum the expression of AQP1 is species-related and predominantly seen in a significant subpopulation of probably sensory submucosal neurons. PMID: 21168316
    4. expression of aquaporins 1, 3, and 8 underlie the high water and urea permeability of the ovine placenta in the last half of pregnancy PMID: 15135229
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    MIP/aquaporin (TC 1.A.8) family
  • 组织特异性：
    Detected in fetal kidney (at protein level). Detected in fetal kidney.
  • 数据库链接：

    KEGG: oas:442999

    UniGene: Oar.889