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  4. Recombinant Saccharomyces cerevisiae Uncharacterized vacuolar membrane protein YJR054W (YJR054W)

Recombinant Saccharomyces cerevisiae Uncharacterized vacuolar membrane protein YJR054W (YJR054W)

  • 中文名称：
    酿酒酵母YJR054W重组蛋白
  • 货号：
    CSB-CF341668SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    YJR054W
  • Uniprot No.：
  • 别名：
    KCH1; YJR054W; J1669; Low affinity K(+ transporter 1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-497
  • 氨基酸序列
    MFNHDWKYSINSKTFADLNIELFRNHKFKTVLNYIIGVVGWNGLKLALFVSDIYTCIKLL AFNSWSNNIIKPYLPFKISKWLFSGCILASIVLLIWEAIAGMRIYKTGNISLTYVNNFSR NLNSVLNYSKFCVYNMIERKGFRQKMTFFTFFQLKDCIRLIFTDTPRQVINGLTLWSVLV TVNKNEDLGDLESFTGLINKIKNIGQTNHEEAVILSLMLFSFIIWALFVFKFLLAVICSI FVYYKIINDQEYSGLREYICVTVSENVDELVERQRKKENDDTIYKTGLLESQTFDDFKEV ENKIETSFNDTSYASNNDSMIELIERRPEYKSQDVCGPIPTMKKTETMESFVDNGNPQYT TRFSAILDSPYINSYESNDIKKAKIQSRSVNTPKYEDLSSSDIFNKIHSAGQLKSTTSME FHGPLDSMPNTTNNIRNFNSNSSRPRPPPLQTKSSINSKADSNDNGRIYTPMKAYFREPD LPRKGLLEDEDRTYNYT
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Low affinity potassium transporter that, with PRM6/KCH2, participates in high-affinity Ca(2+) influx system (HACS) activation during the response to mating pheromone. Directly promotes K(+) influx and HACS may electrochemically respond to this K(+) influx. KCH1 and KCH2 act at the apex of the calcium signaling pathway that is used for survival during prolonged exposures to mating pheromones.
  • 基因功能参考文献：
    1. These data demonstrate that the Kch1 and Kch2 proteins significantly contribute to the maintenance of optimal cation homeostasis and membrane potential in Saccharomyces cerevisiae but not in Candida albicans. PMID: 28810704
    2. Kch1 family proteins represent a conserved linkage between HACS and only certain classes of ER stress in these yeasts. PMID: 24142703
    3. Kch1 and Kch2 directly promote potassium influx and calcium signaling may electrochemically respond to potassium influx. PMID: 23204190
  • 亚细胞定位：
    Vacuole membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 数据库链接：

    KEGG: sce:YJR054W

    STRING: 4932.YJR054W