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  4. Recombinant Saccharomyces cerevisiae Protein CCC1 (CCC1)

Recombinant Saccharomyces cerevisiae Protein CCC1 (CCC1)

  • 中文名称：
    Recombinant Saccharomyces cerevisiae Protein CCC1(CCC1)
  • 货号：
    CSB-CF341728SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    CCC1
  • Uniprot No.：
  • 别名：
    CCC1; YLR220W; L8083.6; Protein CCC1; Cross-complementer of CSG1 protein 1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-322
  • 氨基酸序列
    MSIVALKNAVVTLIQKAKGSGGTSELGGSESTPLLRGSNSNSSRHDNLSSSSSDIIYGRN SAQDLENSPMSVGKDNRNGDNGSDNEKANLGFFQSVDPRVISDLIIGLSDGLTVPFALTA GLSSLGDAKLVITGGFAELISGAISMGLGGYLGAKSESDYYHAEVKKEKRKFYDNSNLIN REIEDILLEINPNFSDETIVSFIKDLQRTPELMVDFIIRYGRGLDEPAENRELISAVTIG GGYLLGGLVPLVPYFFVSDVGTGLIYSIIVMVVTLFWFGYVKTKLSMGSGSSTSKKVTEG VEMVVVGGVAAGAAWFFVKLLG
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals.
  • 基因功能参考文献：
    1. The identification of multiple independent transcriptional pathways that regulate the levels of Ccc1 under high iron conditions accentuates the importance of protecting cells from the toxic effects of high iron PMID: 29043483
    2. Data suggest that SNF1 deletion acts synergistically with YAP5 deletion to regulate transcription of vacuolar iron importer CCC1 and to regulate iron resistance; SNF1 deletion with MSN2/MSN4 deletion results in additive effects on CCC1 transcription. (SNF1 = sucrose non-fermenting kinase 1; YAP5 = transcription factor YAP5; CCC1 = Ca(II)-sensitive cross-complementer 1; MSN = stress-responsive transcriptional activator) PMID: 28760824
  • 亚细胞定位：
    Golgi apparatus membrane. Vacuole membrane; Multi-pass membrane protein.
  • 蛋白家族：
    CCC1 family
  • 数据库链接：

    KEGG: sce:YLR220W

    STRING: 4932.YLR220W