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  4. Recombinant Saccharomyces cerevisiae Peroxisome assembly protein 22 (PEX22)

Recombinant Saccharomyces cerevisiae Peroxisome assembly protein 22 (PEX22)

  • 中文名称：
    酿酒酵母PEX22重组蛋白
  • 货号：
    CSB-CF336615SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    PEX22
  • Uniprot No.：
  • 别名：
    PEX22; YAL055W; Peroxisome assembly protein 22; Peroxin-22
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-180
  • 氨基酸序列
    MPPPSRSRINKTRTLGIVGTAIAVLVTSYYIYQKVTSAKEDNGARPPEGDSVKENKKARK SKCIIMSKSIQGLPIKWEEYAADEVVLLVPTSHTDGSMKQAIGDAFRKTKNEHKIIYCDS MDGLWSCVRRLGKFQCILNSRDFTSSGGSDAAVVPEDIGRFVKFVVDSDVEDVLIDTLCN
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in peroxisome biogenesis.
  • 基因功能参考文献：
    1. mutation, causing Pex22p dysfunction, was sufficient to confer increased malate productivity and dimethyl succinate sensitivity to yeast cells PMID: 28919252
    2. The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor (Pex5). PMID: 25162638
    3. The Pex4p:Pex22p assembly, and not Pex4p alone, functions as the E2 enzyme required for Pex5p ubiquitination. This is a novel mechanism of E2 enzyme regulation. PMID: 22085930
    4. The N-domain of Pex22p can functionally replace the Pex3p N-domain in targeting and peroxisome formation. PMID: 19017643
  • 亚细胞定位：
    Peroxisome membrane; Single-pass membrane protein.
  • 蛋白家族：
    Peroxin-22 family
  • 数据库链接：

    KEGG: sce:YAL055W

    STRING: 4932.YAL055W