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  4. Recombinant Saccharomyces cerevisiae Copper transport protein CTR2 (CTR2)

Recombinant Saccharomyces cerevisiae Copper transport protein CTR2 (CTR2)

  • 中文名称：
    Recombinant Saccharomyces cerevisiae Copper transport protein CTR2(CTR2)
  • 货号：
    CSB-CF334488SVG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    CTR2
  • Uniprot No.：
  • 别名：
    CTR2; YHR175W; Copper transport protein CTR2; Copper transporter 2
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-189
  • 氨基酸序列
    MDDKKTWSTVTLRTFNQLVTSSLIGYSKKMDSMNHKMEGNAGHDHSDMHMGDGDDTCSMN MLFSWSYKNTCVVFEWWHIKTLPGLILSCLAIFGLAYLYEYLKYCVHKRQLSQRVLLPNR SLTKINQADKVSNSILYGLQVGFSFMLMLVFMTYNGWLMLAVVCGAIWGNYSWCTSYSPE IDDSSLACH
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Provides bioavailable copper via mobilization of vacuolar copper stores and export to the cytoplasm.
  • 基因功能参考文献：
    1. Transcription of CTR2 driven by the GPD promoter, which is not identical to the CTR2 promoter, affects degradation of the transcripts by nonsense-mediated mRNA decay pathway. PMID: 25257758
    2. CTR2 plays a role in regulating the level of copper in the cytoplasm. Copper tolerance by the upf1Delta mutant is dependent on the presence of CTR2. PMID: 23450501
    3. demonstrate that copper transporter Ctr2 mobilizes vacuolar copper stores in a manner dependent on conserved amino acid residues PMID: 15494390
    4. Ctr2-1, a mutant form of Ctr2 that mislocalizes to the plasma membrane, requires the Fre1 plasma membrane metalloreductase for Cu(I) import. PMID: 17553781
  • 亚细胞定位：
    Vacuole membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Copper transporter (Ctr) (TC 1.A.56) family, SLC31A subfamily
  • 数据库链接：

    KEGG: sce:YHR175W

    STRING: 4932.YHR175W