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  4. Recombinant Rat Uncharacterized aarF domain-containing protein kinase 4 (Adck4)

Recombinant Rat Uncharacterized aarF domain-containing protein kinase 4 (Adck4)

  • 中文名称：
    Recombinant Rat Uncharacterized aarF domain-containing protein kinase 4(Adck4)
  • 货号：
    CSB-CF738131RA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Coq8b
  • Uniprot No.：
  • 别名：
    Coq8b; Adck4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-528
  • 氨基酸序列
    MWLELGAMLRTTCGPLGRAVRLPCAGALRLRPHWWGPCRDCLAQRVHQDQPGRGLTEDEI RRAREARLRKAPRPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPGGS LQHEGSSPFLTEANAERIVQTLCTVRGAALKIGQMLSIQDNSLISPQLQRVFERVRQSAD FMPRWQMMKVLEEELGKDWQDKVASLEEVPFAAASIGQVHQGVLKDGTEVAVKIQYPGVA ESIQSDVQNLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYRREAACAQTFKKLLADD PFFRVPAVVEELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFM QTDPNWANFLYDASSHKVTLLDFGASRAFGTEFTDHYIEVVKAAADGDRDRVLQKSQDLK FLTGFETKAFSDAHVEAVMILGEPFAASGSYDFGAGETARRIQGLIPVLLRHRLRPPPEE TYALHRKLAGAFLACARLHAHIACRDLFQDTYHRYWASRQTLPLPAAS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.
  • 亚细胞定位：
    Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.
  • 蛋白家族：
    Protein kinase superfamily, ADCK protein kinase family
  • 组织特异性：
    In the kidney, expressed in glomeruli, predominantly in podocyte foot precesses, as well as in proximal tubules and collecting ducts (at protein level).
  • 数据库链接：

    KEGG: rno:308453

    STRING: 10116.ENSRNOP00000028290

    UniGene: Rn.11549