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  4. Recombinant Rat Mas-related G-protein coupled receptor member A (Mrgpra)

Recombinant Rat Mas-related G-protein coupled receptor member A (Mrgpra)

  • 中文名称：
    大鼠Mrgpra重组蛋白
  • 货号：
    CSB-CF759717RA
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Mrgpra
  • Uniprot No.：
  • 别名：
    Mrgpra; Mrga; Mas-related G-protein coupled receptor member A
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-304
  • 氨基酸序列
    MDKTIPGSFNSRTLIPNLLIIISGLVGLIGNAMVFWLLGFRLARNAFSVYILNLALADFL FLLCHIIDSTLLLLKFSYPNIIFLPCFNTVMMVPYIAGLSMLSAISTERCLSVVCPIWYR CRRPKHTSTVMCSAIWVLSLLICILNRYFCGFLDTKYEKDNRCLASNFFTAACLIFLFVV LCLSSLALLVRLFCGAGRMKLTRLYATIMLTVLVFLLCGLPFGIHWFLLIWIKIDYGKFA YGLYLAALVLTAVNSCANPIIYFFVGSFRHQKHQTLKMVLQRALQDTPETAENTVEMSSS KVEP
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception.
  • 基因功能参考文献：
    1. Kinetics of adenine binding to the adenine receptor of the rat brain cortex. PMID: 15604413
    2. Results validate the predicted structure for MrgA and should be useful for seeking other small molecule agonists and antagonists. PMID: 17728165
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Mas subfamily
  • 组织特异性：
    Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
  • 数据库链接：

    KEGG: rno:252960

    STRING: 10116.ENSRNOP00000019051

    UniGene: Rn.81069