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  4. Recombinant Mouse UDP-glucuronosyltransferase 1-6 (Ugt1a6)

Recombinant Mouse UDP-glucuronosyltransferase 1-6 (Ugt1a6)

  • 中文名称：
    小鼠Ugt1a6重组蛋白
  • 货号：
    CSB-CF723742MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Ugt1a6
  • Uniprot No.：
  • 别名：
    Ugt1a6; Ugt1; Ugt1a6a; Ugt1a7; UDP-glucuronosyltransferase 1-6; UDPGT 1-6; UGT1*6; UGT1-06; UGT1.6; Phenol UDP-glucuronosyltransferase; UDP-glucuronosyltransferase 1A6; UGT1A6; UGP1A1; UGT1A7
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    27-531
  • 氨基酸序列
    DKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKIFSVTYSLEE LQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSATLSFLRENKFDA LFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFP QRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPV MPNMIFLGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGR IPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPM VMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHK DRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK CCAYGCRKCFGGKGRVKKSHKSKTH
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Conjugates small planar phenolic molecules such as 4-nitrophenol, 1-naphthol, and 4-methylumbelliferone. The bulky phenol 4-hydroxybiphenyl, androgens and estrogens are not substrates. 2-hydroxybiphenyl is an excellent substrate.
  • 基因功能参考文献：
    1. the difference in expression levels between Ugt1a6a and Ugt1a6b in the hippocampus led us to speculate that Ugt1a6a is likely the predominant catalyst of serotonin glucuronidation in the mouse brain. PMID: 23089803
  • 亚细胞定位：
    Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    UDP-glycosyltransferase family
  • 组织特异性：
    Expressed in liver, kidney and at very low levels in colon.
  • 数据库链接：

    KEGG: mmu:94284

    STRING: 10090.ENSMUSP00000014263

    UniGene: Mm.300095