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  4. Recombinant Mouse Regulator of microtubule dynamics protein 3 (Fam82a2)

Recombinant Mouse Regulator of microtubule dynamics protein 3 (Fam82a2)

  • 中文名称：
    小鼠Rmdn3重组蛋白
  • 货号：
    CSB-CF663665MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Rmdn3
  • Uniprot No.：
  • 别名：
    Rmdn3; Fam82a2; Fam82c; Regulator of microtubule dynamics protein 3; RMD-3; mRMD-3; Protein FAM82A2; Protein FAM82C
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-470
  • 氨基酸序列
    MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRSHSLPNSLDYAQASERG RQVTQFRAIPGEAGDAAILPSLSQEGQEKVLDRLDFVLTSLMALRREVEELQRSLQGLAG EIVGEVRSHIEENQRVARRRRFPFARERSDSTGSSSVYFTASSGAALTDAESEGGYTTAN AESDYERDSDKESGDAEDEVSCETVRMGRKDSLDLDVEAASSPAAAALEEDDSSGREDVQ LVLLQADELHQGSKQDKREGFQLLLNNKLAYGSRQDFLWRLARAYSDMSDLTEEESGKKS YALNGKEEAEAALKKGDESAACHLWYAVLCGQLAEHEGISKRIQSGFSFKEHVDKAIELQ PEDPRGHFLLGRWCYQVSHLNWLEKKTATALFESPLSATVQDALQSFLKAEELQPGFSKA GRVYISKCYRELGKNSEARKWMKLAQELPDVTNEDSAFQKDLEELEVILG
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
  • 基因功能参考文献：
    1. PTPIP51 as a therapeutic target for ischemic heart diseases. PMID: 28345618
    2. Protein interaction profile of PTPIP51 suggests a role in the memory formation in the hippocampus and cerebellum. PMID: 25496818
    3. PTPIP51(protein tyrosine phosphatase interacting protein 51) might serve as a linking protein in adipocyte metabolism by connecting the insulin receptor-triggered lipogenesis with the protein kinase A-dependent lipolysis. PMID: 23533724
    4. The interaction of PTPIP51 with 14-3-3beta, especially in trained individuals, hints to an involvement of PTPIP51 in the downstream regulation of insulin action. PMID: 21266951
    5. Includes the study of an upstream ORF in this gene, and shows that it functions to reduce protein levels by ~79%. PMID: 19372376
    6. The data presented here suggest a role of PTPIP51 in neuronal homeostasis, axonal growth, and transport. PMID: 19844996
    7. The PTPIP51 was integrated in signaling cascades regulating differentiation and apoptosis during eye development. PMID: 18084773

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  • 亚细胞定位：
    Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    RMDN family
  • 数据库链接：

    KEGG: mmu:67809

    STRING: 10090.ENSMUSP00000092283

    UniGene: Mm.475909