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  4. Recombinant Mouse Protein FAM57B (Fam57b)

Recombinant Mouse Protein FAM57B (Fam57b)

  • 中文名称：
    小鼠Fam57b重组蛋白
  • 货号：
    CSB-CF763170MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Fam57b
  • Uniprot No.：
  • 别名：
    Tlcd3b; Fam57b; Ceramide synthase; Protein FAM57B; TLC domain-containing protein 3B
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-275
  • 氨基酸序列
    MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVS TSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGEDGTPRALGSTWA VVRGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQ YKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLSVPMAIPAHVNLGAAL LLAPQLYWFFLICRGACRLFRPRGSPPPSPCQTQD
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in ceramide synthesis. In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity. May interfere with adipogenesis by stimulating ceramide synthesis.
  • 基因功能参考文献：
    1. PPARgamma regulates Fam57b transcription during the adipogenesis of ST2 cells PMID: 23275342
  • 亚细胞定位：
    [Isoform 1]: Golgi apparatus membrane; Multi-pass membrane protein.; [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.; [Isoform 3]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 组织特异性：
    Each isoform has a distinct expression pattern. Isoform 1 is highly expressed in brain. Isoform 2 is expressed at low levels, if any, in all analyzed tissues, with slightly higher levels in testis. Isoform 3 is expressed at very high levels in testis and,
  • 数据库链接：

    KEGG: mmu:68952

    STRING: 10090.ENSMUSP00000078392

    UniGene: Mm.440393