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  4. Recombinant Mouse Ganglioside-induced differentiation-associated protein 1 (Gdap1)

Recombinant Mouse Ganglioside-induced differentiation-associated protein 1 (Gdap1)

  • 中文名称：
    小鼠Gdap1重组蛋白
  • 货号：
    CSB-CF009338MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Gdap1
  • Uniprot No.：
  • 别名：
    Gdap1; Ganglioside-induced differentiation-associated protein 1; GDAP1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-358
  • 氨基酸序列
    MARRQDEARAGVPLRVEGPPDKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPL SEHNEPWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPR VQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPD LQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGNQPWLC GESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLETYYERVLKRKTFNKVLGHVNNIL ISAVLPTAFRVAKKRAPKVLGSTLVVGLLVGMGYFAFMLFRRRLGSMILALRPRPNYF
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates the mitochondrial network by promoting mitochondrial fission.
  • 基因功能参考文献：
    1. absence of GDAP1 induces a peripheral neuropathy with loss of motor neurons, mitochondrial defects and abnormal calcium homeostasis. PMID: 25860513
    2. Members of the GDAP1 family are responsive and protective against stress associated with increased levels of oxidized glutathione. PMID: 24480485
    3. Cell expression of Gdap1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease are reported. PMID: 18021315
  • 亚细胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族：
    GST superfamily
  • 组织特异性：
    Expressed in brain, spinal cord, muscles and intestinal villi. In the central nervous system expressed most prominently in the cortex, cerebellum, thalamus, olfactory bulb, and spinal cord. Expressed also in sciatic nerves and in dorsal root ganglia.
  • 数据库链接：

    KEGG: mmu:14545

    STRING: 10090.ENSMUSP00000026879

    UniGene: Mm.18218