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  4. Recombinant Mouse Formyl peptide receptor-related sequence 1 (Fpr-s1)

Recombinant Mouse Formyl peptide receptor-related sequence 1 (Fpr-s1)

  • 中文名称：
    小鼠Fpr-s1重组蛋白
  • 货号：
    CSB-CF515507MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Fpr-s1
  • Uniprot No.：
  • 别名：
    Fpr-s1; Fpr2; Fpr3; Fprl1; Lxa4r; Formyl peptide receptor-related sequence 1; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor related sequence 1; Formyl peptide receptor-like 1; Lipoxin A4 receptor; LXA4 receptor; N-formyl peptide receptor 2; N-formyl peptide receptor 3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-351
  • 氨基酸序列
    METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVT TIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIA LDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSF VSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPF RVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPI LYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states.
  • 基因功能参考文献：
    1. ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance PMID: 27207555
    2. The genome of at least 19 strains encodes a non-functional Fpr3 variant, whereas at least 13 other strains express an intact receptor. These results provide a foundation for understanding the in vivo function of Fpr3. PMID: 26957543
    3. the ligand profile of mFpr-rs1 is consistent with a role in vomeronasal pathogen sensing PMID: 22859307
    4. lipoxin A(4)mediated the restoration of homeostasis of inflammation perpetuated by blocking COX-2 activity and PGE(2) production during resolution of collagen-induced arthritis PMID: 20435922
    5. This homologue receptor shows 89% sequence identity with murine lipoxin A4 receptor cDNA and functionally responds to LXA4 as a ligand. PMID: 12218158

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Expressed exclusively in vomeronasal neurons. Expressed in 0.6 % of a subset of sensory neurons located in the basal layer of the vomeronasal organ. Each neuron appears to express only one receptor gene. Expressed mostly in neutrophils, followed by spleen
  • 数据库链接：

    KEGG: mmu:14294

    STRING: 10090.ENSMUSP00000093316

    UniGene: Mm.378918