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  4. Recombinant Mouse CKLF-like MARVEL transmembrane domain-containing protein 2A (Cmtm2a)

Recombinant Mouse CKLF-like MARVEL transmembrane domain-containing protein 2A (Cmtm2a)

  • 中文名称：
    Recombinant Mouse CKLF-like MARVEL transmembrane domain-containing protein 2A(Cmtm2a)
  • 货号：
    CSB-CF861595MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    Cmtm2a
  • Uniprot No.：
  • 别名：
    Cmtm2a; Cklfsf2a; CKLF-like MARVEL transmembrane domain-containing protein 2A; Chemokine-like factor superfamily member 2A
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-169
  • 氨基酸序列
    MAAPIKFPFRPRGGQPREDTTPKRGLRRYLLELKESNKEFWLSGHAVFKLLSLGCMISAL DYFETMLPHPVLILLICMEAAICIFFIFLNTLAINRYIPFVFWPMADIFNSLFSCVFLGG GIYFAFKARRLLPKPYLTAMILMGAAAICSFIDMLLQFQHFRGLRLRKW
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Taken together, these results suggest that ARR19 may play an important role in the differentiation of male reproductive organs such as testis and prostate PMID: 26260329
    2. Concluding, the temporal expression pattern of CKLF1 was coincident with the postnatal developmental stages and the spatial locations of CKLF1 were some destinations of neural cell migration or regions where myelination normally occurs. PMID: 22587964
    3. ARR19 acts as a novel coregulator of Nur77, in turn regulating Nur77-induced testicular steroidogenesis. PMID: 20472563
    4. Overexpression of chemokine-like factor 2 promotes the proliferation and survival of C2C12 skeletal muscle cells. PMID: 12183067
    5. ARR19 may act as an androgen receptor corepressor in vivo and play an important role in male reproductive functions PMID: 14576337
    6. Results show that mouse chemokine-like factors (CKLF) 2, 4, 5 and 6 are four splicing variants which are homologues of human CKLFs, and that murine CKLFs possess distinct features compared to their human counterparts. PMID: 14672409
    7. Data show that mouse Cklfsf2a and Cklfsf2b are two homologues of human CKLFSF2. PMID: 16343975
    8. ARR19 gene expression in testicular Leydig cells is regulated by luteinizing hormone/cAMP signaling via the control of GATA-1 expression, resulting in the control of testicular steroidogenesis PMID: 19398553

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Chemokine-like factor family
  • 数据库链接：

    KEGG: mmu:73381

    STRING: 10090.ENSMUSP00000034344

    UniGene: Mm.272746