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Recombinant Mesocricetus auratus 3 beta-hydroxysteroid dehydrogenase type 3 (HSD3B3)

  • 中文名称：
    Recombinant Mesocricetus auratus 3 beta-hydroxysteroid dehydrogenase type 3(HSD3B3)
  • 货号：
    CSB-CF522050MRG
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    HSD3B3
  • Uniprot No.：
  • 别名：
    HSD3B3; NADPH-dependent 3-keto-steroid reductase HSD3B3; 3 beta-hydroxysteroid dehydrogenase type 3; 3 beta-hydroxysteroid dehydrogenase type III; 3 beta-HSD III; Dihydrotestosterone 3-ketoreductase
  • 种属：
    Mesocricetus auratus (Golden hamster)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-373
  • 氨基酸序列
    PAWSCLVTGAGGFLGQRIIRMLAQEKELQEVRTLFRSFTPKHREELSKLQTKTKVTVLEG DILDAQCLRRACQGISVVIHTAAAIDVFGAIPRQTVIDINLKGTQHLLDACIGARVPVFI YSSSVAVAGPNSYKVIIQNGSEEENHESTWSDPYAYSKKMAEKAVLAANGSTLKDGGTLH TCALRLPFIYGEKSKFISDTMDRALKNNGLINGFSRFSVISSVYVNNAAWAHVLAARGLQ DPKKSPNIQGQFYYISDDTPHQSYDDLCYTLSKDWGLRPDSSWKPPVALLYWFGFLLETV SFLLRPVYNYQPPFNRHLVTLLNSVFTFSYKKAQRDLGYEPLVSWEEAREKTSEWIGSLV EQHKGTLNIKAQ
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Does not function as an isomerase.
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
  • 蛋白家族：
    3-beta-HSD family
  • 组织特异性：
    High levels in adrenal gland, kidney and male liver (at protein level). Low levels in female liver (at protein level). Expressed in ovaries (at protein level).