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  4. Recombinant Drosophila willistoni Protein wntless (wls)

Recombinant Drosophila willistoni Protein wntless (wls)

  • 中文名称：
    Recombinant Drosophila willistoni Protein wntless(wls)
  • 货号：
    CSB-CF453828DMQ
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    wls
  • Uniprot No.：
  • 别名：
    wls; GK20551; Protein wntless
  • 种属：
    Drosophila willistoni (Fruit fly)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    36-562
  • 氨基酸序列
    APVPAGHLTILGSLCRENHARQNDTNFFLYSRGDGACKQVTSEEVDADALKLANQIVHVF QLPLPRENKILEYTRWQQNLIGVLQVEFGYDSSPELHEPAKELQLTIDMRLAYRNNDDAD NDWKLYAHSVEHRYLDCDTSHIGPTETLYTCDMIPLFELGALHHSFYLLNLRFPLDSPKQ MNLQFGHMHDLTLTAIHQNGGFTKVWLFLKSVLFPFVVGIMVWFWRRVHLLQRSPALLEY MLIYLGGALTFLNLPLEYLTLGLEMPYMLLLSDIRQGIFYAMLLSFWLIFAGEHMLIQDS GNKSTIRSRYWKHLSAVVVGCISLFIFDISERGVQLRNPFYSIWTTPLGAKVAMGFIFLA GVSAAIYFLFLCFMIWKVFKNIGDKRTSLPSMSQARRLHYEGLIYRFKFLMLATLLCAAL TVAGFIMGQMAEGHWKWNEHIEIQLTSAFLTGVYGMWNIYIFALLILYAPSHKQWPSMHH SDETTQSNENIVASAASEEIEFSHLPSDSNPSEISSLTSFTRKVAFD
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip.
  • 亚细胞定位：
    Cell junction, synapse, presynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Wntless family
  • 数据库链接：

    KEGG: dwi:Dwil_GK20551

    STRING: 7260.FBpp0249694