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  4. Recombinant Bovine V-type proton ATPase subunit S1 (ATP6AP1)

Recombinant Bovine V-type proton ATPase subunit S1 (ATP6AP1)

  • 中文名称：
    Recombinant Bovine V-type proton ATPase subunit S1(ATP6AP1)
  • 货号：
    CSB-CF002382BO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    ATP6AP1; ATP6IP1; ATP6S1; V-type proton ATPase subunit S1; V-ATPase subunit S1; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; Vacuolar proton pump subunit S1
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    36-468
  • 氨基酸序列
    ATSEQQVPLVLWSSDRGLWAPAADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLS IEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLH VDLATLQELKLNASIPALLLIRLPYTASSGLMAPKEVLMGNDEVIGQVLSTLKSEDIPYT AALTAVRPSRVARDVAMVTGGLGRQLLQRTVVPPTMNVPVSYNDSYDTRILFWAQNFSVA YGEHWEDLTSRTFGVQDLNLTGSFWNDTVARLVLTYDSLFGTMVTFKFILANSYYSVSAR HWFTLENLEIHSNGSVAYFNASQVTGPSIYSFHCEHVSSENEDGNLLVPDTQPSLWQMTF RDFQIQAFNVTDKKFSYASDCAGFFSPGIWMGLLTSLFMLFIFTYGLHMILSLKTMDRFD DHKGPTITLTQIV
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca(2+)-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane.
  • 蛋白家族：
    Vacuolar ATPase subunit S1 family
  • 数据库链接：

    KEGG: bta:327687

    STRING: 9913.ENSBTAP00000016073

    UniGene: Bt.4442