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  4. Recombinant Bovine Transmembrane 4 L6 family member 5 (TM4SF5)

Recombinant Bovine Transmembrane 4 L6 family member 5 (TM4SF5)

  • 中文名称：
    牛TM4SF5重组蛋白
  • 货号：
    CSB-CF640669BO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
    TM4SF5
  • Uniprot No.：
  • 别名：
    TM4SF5; Transmembrane 4 L6 family member 5
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-196
  • 氨基酸序列
    MCTGKCARFVGLSLIPLSLVCIVANALLLVPNGQTTWTKDHLSLQVWLMAGFVGGGLMVL CPGISAVRAGGKGCCGAGCCGNRCRMLRSVFCSAIGLLGAIYCLSVSGTGLRIGPQCLMN GSWDYHFQDTAGSYLLNRTQWNLCVEPPDVVLWNVTLFSLLVAASCLEILLCGVQLVNAS IGVLCGDCRKKQGSSQ
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a lysosomal membrane arginine sensor. Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations. Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus. CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression.
  • 亚细胞定位：
    Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    L6 tetraspanin family
  • 数据库链接：

    KEGG: bta:511869

    STRING: 9913.ENSBTAP00000004861

    UniGene: Bt.20586