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  4. Recombinant Xenopus laevis Cytochrome P450 26A1 (cyp26a1)

Recombinant Xenopus laevis Cytochrome P450 26A1 (cyp26a1)

  • 中文名称：
    Recombinant Xenopus laevis Cytochrome P450 26A1(cyp26a1),Yeast
  • 货号：
    CSB-YP006402XBE
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Cytochrome P450 26A1(cyp26a1),Yeast
  • 货号：
    CSB-EP006402XBE
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Cytochrome P450 26A1(cyp26a1),Yeast
  • 货号：
    CSB-EP006402XBE-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Cytochrome P450 26A1(cyp26a1),Yeast
  • 货号：
    CSB-BP006402XBE
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Xenopus laevis Cytochrome P450 26A1(cyp26a1),Yeast
  • 货号：
    CSB-MP006402XBE
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    cyp26a1
  • Uniprot No.：
  • 别名：
    cyp26a1; cyp26Cytochrome P450 26A1; EC 1.14.13.-; Retinoic acid-converting enzyme; RACE; Retinoic acid-degrading enzyme CYP26; xCYP26
  • 种属：
    Xenopus laevis (African clawed frog)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-492
  • 氨基酸序列
    MDLYTLLTSA LCTLALPLLL LLTAAKLWEV YCLRRKDAAC ANPLPPGTMG LPFFGETLQM VLQRRRFLQV KRSQYGRIYK THLFGSPTVR VTGAENVRQI LMGEHKLVSV HWPASVRTIL GAGCLSNLHD NEHKYTKKVI AQAFSREALA NYVPQMEEEV RCSVNLWLQS GPCVLVYPAI KRMMFRIAMR LLLGCDPQRM DREQEETLLE AFEEMSRNLF SLPIDVPFSG LYRGLRARNL IHAQIEENIK EKLQREPDEH CKDALQLLID YSRRNGEPIN LQALKESATE LLFGGHGTTA SAATSLTSFL ALHKDVLEKV RKELETQGLL STKPEEKKEL SIEVLQQLKY TSCVIKETLR LSPPVAGGFR VALKTFVLNG YQIPKGWNVI YSIADTHGEA DLFPDTDKFN PDRFLTPLPR DSSRFGFIPF GGGVRCCIGK EFAKILLKVF VVELCRNCDW ELLNGSPAMT TSPIICPVDN LPAKFKPFSS SI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. May regulate at-RA signaling during hindbrain development. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers. May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid.
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 组织特异性：
    Expressed primarily in ovary, brain and eyes.
  • 数据库链接：

    UniGene: Xl.456