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  4. Recombinant Vaccinia virus Serine proteinase inhibitor 3 (SPI-3)

Recombinant Vaccinia virus Serine proteinase inhibitor 3 (SPI-3)

  • 货号：
    CSB-YP322434VAI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP322434VAI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP322434VAI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP322434VAI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP322434VAI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SPI-3
  • Uniprot No.：
  • 别名：
    SPI-3; VACWR033; K2L; Protein K2; Serine proteinase inhibitor 3
  • 种属：
    Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    16-369
  • 氨基酸序列
    YRLQG FTNAGIVAYK NIQDDNIVFS PFGYSFSMFM SLLPASGNTR IELLKTMDLR KRDLGPAFTE LISGLAKLKT SKYTYTDLTY QSFVDNTVCI KPSYYQQYHR FGLYRLNFRR DAVNKINSIV ERRSGMSNVV DSNMLDNNTL WAIINTIYFK GIWQYPFDIT KTRNASFTNK YGTKTVPMMN VVTKLQGNTI TIDDEEYDMV RLPYKDANIS MYLAIGDNMT HFTDSITAAK LDYWSFQLGN KVYNLKLPKF SIENKRDIKS IAEMMAPSMF NPDNASFKHM TRDPLYIYKM FQNAKIDVDE QGTVAEASTI MVATARSSPE KLEFNTPFVF IIRHDITGFI LFMGKVESP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Prevents cell to cell fusion via its interaction with A56 protein. The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation.
  • 基因功能参考文献：
    1. The SPI-3/A56 complex on the infected cell surface therefore appears to reduce the entry of virions into infected cells. PMID: 18760436
    2. The s have shown that A56/K2 is sufficient to prevent virus entry and fusion as well as formation of syncytia through interaction with the entry/fusion complex. PMID: 19036815
  • 亚细胞定位：
    Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Extracellular side. Note=Component of extracellular enveloped virus (EEV) but not intracellular mature virus (IMV). Anchored to the surface of the outermost membrane of EEV via its interaction with A56 protein.
  • 蛋白家族：
    Serpin family, Poxviruses subfamily
  • 数据库链接：

    KEGG: vg:3707648