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  4. Recombinant Vaccinia virus Protein A26 (VACWR149)

Recombinant Vaccinia virus Protein A26 (VACWR149)

  • 货号：
    CSB-YP328495VAI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP328495VAI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP328495VAI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP328495VAI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP328495VAI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    VACWR149
  • Uniprot No.：
  • 别名：
    VACWR149; A26LProtein A26
  • 种属：
    Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-500
  • 氨基酸序列
    MANIINLWNG IVPTVQDVNV ASITAFKSMI DETWDKKIEA NTCISRKHRN IIHEVIRDFM KAYPKMDENK KSPLGAPMQW LTQYYILKNE YHKTMLAYDN GSLNTKFKTL NIYMITNVGQ YILYIVFCII SGKNHDGTPY IYDSEITSND KNFINERIKY ACKQILHGQL TIALRIRNKF MFIGSPMYLW FNVNGSQVYH DIYDRNAGFH NKEIGRLLYA FMYYLSISGR FLNDFALLKF TYLGESWTFS LSVPEYILYG LGYSVFDTIE KFSNDAILVY IRTNNRNGYD YVEFNKKGIA KVTEDKPDND KRIHAIRLIN DSTDVQHIHF GFRNMVIIDN ECANIQSSAE NATDTGHHQD SKINIEVEDD VIDDDDYNPK PTPIPEPHPR PPFPRHEYHK RPKLLPVEEP DPVKKDADRI RLDNHILNTL DHNLNFIGHY CCDTAAVDRL EHHIETLGQY AVILARKINM QTLLFPWPLP TVHPHAIDGS IPPHGRSTIL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in bridging the mature virion with structural protein A25. Presence of protein A26 in the virion structurally prevents direct virus-cell fusion mechanism.
  • 基因功能参考文献：
    1. This study reveals a new property of vaccinia virus A26, which is in regulating host antiviral innate immunity in vitro and in vivo. PMID: 28659486
    2. Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein. PMID: 23990784
    3. A26 protein binds to A16 and G9 proteins and dissociates from mature virions at low pH. PMID: 22278246
  • 亚细胞定位：
    Virion membrane. Note=A26 is anchored to the mature virion (MV) membrane through disulfide bonding with protein A27.
  • 蛋白家族：
    Chordopoxvirinae A26 protein family
  • 数据库链接：

    KEGG: vg:3707679