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  4. Recombinant Sheep Transcription factor AP-2-alpha (TFAP2A)

Recombinant Sheep Transcription factor AP-2-alpha (TFAP2A)

  • 中文名称：
    绵羊TFAP2A重组蛋白
  • 货号：
    CSB-YP865041SH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    绵羊TFAP2A重组蛋白
  • 货号：
    CSB-EP865041SH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    绵羊TFAP2A重组蛋白
  • 货号：
    CSB-EP865041SH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    绵羊TFAP2A重组蛋白
  • 货号：
    CSB-BP865041SH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    绵羊TFAP2A重组蛋白
  • 货号：
    CSB-MP865041SH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TFAP2A
  • Uniprot No.：
  • 别名：
    TFAP2ATranscription factor AP-2-alpha; AP2-alpha; AP-2 transcription factor; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2
  • 种属：
    Ovis aries (Sheep)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-491
  • 氨基酸序列
    MPPRLASVKI PYDWGRKGPF RFWRIFCQSR AVGWFLAAAC GRAGRFRTQP AEWPTPDAVF SPLGLALFQD RHDGASNGTA RLPQLGTVGQ SPYTSAPPLS HTPNADFQPP YFPPPYQPIY PQSQDPYSHV NDPYSLNPLH AQPQPQHPGW PGQRQSQESG LLHTHRGLPH QLSGLDPRRD YRRHEDLLHG PHGLGSGLGD LPIHSLPHAI EDVPHVEDPG INIPDQTVIK KGPVSLSKSN SNAVSSIPIN KDNLFGGVVN PNEVFCSVPG RLSLLSSTSK YKVTVAEVQR RLSPPECLNA SLLGGVLRRA KSKNGGRSLR EKLDKIGLNL PAGRRKAANV TLLTSLVEGE AVHLARDFGY VCETEFPAKA VAEFLNRQHS DPNEQVTRKN MLLATKQICK EFTDLLAQDR SPLGNSRPNP ILEPGIQSCL THFNLISHGF GSPAVCAAVT ALQNYLTEAL KAMDKMYLSN NPNSHTDNSA KSSDKEEKHR K
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
  • 基因功能参考文献：
    1. AP-2 is likely to play an important role in the modulation of COX-1 gene expression by E2 via protein-DNA interaction involving AP-2alpha & ERalpha at a proximal regulatory element in the Cox-1 promoter. PMID: 15705965
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    AP-2 family
  • 数据库链接：

    KEGG: oas:443109

    UniGene: Oar.827