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  4. Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide (ADCYAP1)

Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide (ADCYAP1)

  • 中文名称：
    Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide(ADCYAP1),Yeast
  • 货号：
    CSB-YP001346SH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide(ADCYAP1),Yeast
  • 货号：
    CSB-EP001346SH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide(ADCYAP1),Yeast
  • 货号：
    CSB-EP001346SH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide(ADCYAP1),Yeast
  • 货号：
    CSB-BP001346SH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Sheep Pituitary adenylate cyclase-activating polypeptide(ADCYAP1),Yeast
  • 货号：
    CSB-MP001346SH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ADCYAP1
  • Uniprot No.：
  • 别名：
    ADCYAP1Pituitary adenylate cyclase-activating polypeptide; PACAP) [Cleaved into: PACAP-related peptide; PRP-48); Pituitary adenylate cyclase-activating polypeptide 27; PACAP-27; PACAP27); Pituitary adenylate cyclase-activating polypeptide 38; PACAP-38; PACAP38)]
  • 种属：
    Ovis aries (Sheep)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    82-129
  • 氨基酸序列
    DVAHGILDK AYRKVLDQLS ARRYLQTLMA KGLGGTPGGG ADDDSEPLS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.
  • 基因功能参考文献：
    1. This study provided a detailed inventory of PACAP influenced gene expressions and protein targets in mice ischemic brain. PMID: 23176072
    2. 2 patients with trisomy 18p with PACAP overexpression and transgenic mice overexpressing PACAP in megakaryocytes have thrombopathy, a mild thrombocytopenia, and a reduced number of mature megakaryocytes in their bone marrow PMID: 18000164
    3. Results demonstrate that PACAP/VIP signaling is trophic and can maintain neural stem/progenitor cells in a multipotent state. PMID: 18629655
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Glucagon family
  • 数据库链接：

    KEGG: oas:443337

    UniGene: Oar.695