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  4. Recombinant Serine/threonine-protein phosphatase 4 catalytic subunit 1 (pph-4.1)

Recombinant Serine/threonine-protein phosphatase 4 catalytic subunit 1 (pph-4.1)

  • 中文名称：
    秀丽隐杆线虫pph-4.1重组蛋白
  • 货号：
    CSB-YP893624CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    秀丽隐杆线虫pph-4.1重组蛋白
  • 货号：
    CSB-EP893624CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    秀丽隐杆线虫pph-4.1重组蛋白
  • 货号：
    CSB-EP893624CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    秀丽隐杆线虫pph-4.1重组蛋白
  • 货号：
    CSB-BP893624CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    秀丽隐杆线虫pph-4.1重组蛋白
  • 货号：
    CSB-MP893624CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    pph-4.1
  • Uniprot No.：
  • 别名：
    pph-4.1; Y75B8A.30; Serine/threonine-protein phosphatase 4 catalytic subunit 1; PP4C-1; EC 3.1.3.16
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-333
  • 氨基酸序列
    MALACTDSAN STFSRVDSPT SGPSDQLTTH DLDRHIEKLM RCELIAEQDV KTLCAKAREI LAEEGNVQVI DSPVTICGDI HGQFYDLMEL FKVGGPVPNT NYLFLGDFVD RGFYSVETFL LLLALKARYP DRMMLIRGNH ESRQITQVYG FYDECLRKYG NASVWKHCTE VFDYLSLAAV IDGKVFCVHG GLSPSISTMD QIRVIDRKQE VPHDGPMCDL LWSDPEEGNV GWGLSPRGAG YLFGADASKT FCETNGVDLI CRAHQLVMEG YKWHFNEKVL TVWSAPNYCY RCGNVAAILE LDENLNKEFT IFEAAPQENR GAPAKKPHAD YFL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulting in chiasma formation. During oocyte meiosis II and probably together with regulatory subunit ppfr-1, may regulate microtubule severing by dephosphorylating and activating mei-1, a component of the katanin microtubule severing complex.
  • 基因功能参考文献：
    1. We show that in Caenorhabditis elegans, PPH-4.1, is required independently to carry out four separate functions involving meiotic chromosome dynamics PMID: 25340746
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族：
    PPP phosphatase family, PP-4 (PP-X) subfamily
  • 数据库链接：

    KEGG: cel:CELE_Y75B8A.30

    STRING: 6239.Y75B8A.30

    UniGene: Cel.19352