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  4. Recombinant Serine/threonine-protein kinase sgk-1 (sgk-1)

Recombinant Serine/threonine-protein kinase sgk-1 (sgk-1)

  • 中文名称：
    布里格萨隐杆线虫sgk-1重组蛋白
  • 货号：
    CSB-YP427477CXX
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    布里格萨隐杆线虫sgk-1重组蛋白
  • 货号：
    CSB-EP427477CXX
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    布里格萨隐杆线虫sgk-1重组蛋白
  • 货号：
    CSB-EP427477CXX-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    布里格萨隐杆线虫sgk-1重组蛋白
  • 货号：
    CSB-BP427477CXX
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    布里格萨隐杆线虫sgk-1重组蛋白
  • 货号：
    CSB-MP427477CXX
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    sgk-1
  • Uniprot No.：
  • 别名：
    sgk-1; CBG16386; Serine/threonine-protein kinase sgk-1; EC 2.7.11.1; Serum- and glucocorticoid-inducible kinase homolog; Serum/glucocorticoid-regulated kinase 1
  • 种属：
    Caenorhabditis briggsae
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-464
  • 氨基酸序列
    MGSLYYSGSR MVRKDEVSCK LVMGDDKKTV VYAVRIGDGP IMQKVYEEYE KFFLTDVKDM VPEKFTIFPK KKLLQSKKTF FEKRRLWIQD VCQHLVDNQT KSEDVCRFFH IEAPDDDDNT VDLGPSERKT ATANDFDFLT TIGKGSFGRV YQVRHKETKK IYAMKVLSKE HIRKKNEVKH VMAERNVLIN NFKHPFLVSL HFSFQNKEKL YFVLDHLNGG ELFSHLQREK HFTESRSRFY AAEIACALGY LHEKNIIYRD LKPENLLLDD KGYLVLTDFG LCKEDMQGSK TTSTFCGTPE YLAPEIILKK PYDKTVDWWC LGSVLYEMIF GLPPFYSKDH NEMYDKIINQ PLRLKHTISV PCTELITGLL QKDRSKRLGH KNDFRDIQDH PFFLPVDWDK LLNRELKAPF IPKVKNAMDI SNISKEFVEI QIDPASLAPQ QLAVTHRDHD FENFTFVDTN RVLV
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating development, stress response, and longevity. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their function. Plays a role in the intracellular trafficking of proteins such as mig-14 to the cell membrane, and this may be through positively regulating ceramide synthesis. Acts downstream of rict-1 to regulate fat storage, size, and development. Downstream of age-1 and together with akt-1/2, promotes cell survival during embryonic development. Does not appear to play a role in immune function.
  • 亚细胞定位：
    Cytoplasm. Nucleus. Apical cell membrane.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 数据库链接：

    STRING: 6238.CBG16386