Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Schizosaccharomyces pombe DNA repair protein rad60 (rad60)

Recombinant Schizosaccharomyces pombe DNA repair protein rad60 (rad60)

  • 中文名称：
    庞贝裂殖酵母rad60重组蛋白
  • 货号：
    CSB-YP891502SXV
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    庞贝裂殖酵母rad60重组蛋白
  • 货号：
    CSB-EP891502SXV
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    庞贝裂殖酵母rad60重组蛋白
  • 货号：
    CSB-EP891502SXV-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    庞贝裂殖酵母rad60重组蛋白
  • 货号：
    CSB-BP891502SXV
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    庞贝裂殖酵母rad60重组蛋白
  • 货号：
    CSB-MP891502SXV
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    rad60
  • Uniprot No.：
  • 别名：
    rad60; SPBC1921.02; DNA repair protein rad60
  • 种属：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-406
  • 氨基酸序列
    MDNLDEDDLA FFSKPIKKPP LNYAKQLIAS SSDSEEESEL DTNKQALEHI NAQKNITHNE NKSAEPLSRQ STILDADEGN QDVSDTTPNA CLNEGRHSPK SAISCVTQPV SPVYNTRAAA NLRNNSINSE AALSTTSSLL DDDFARRLEE IDRQVQEFEK SSSDMDVQIH THKREIEEDD DNTSADVPLL KHSKSDHSTL YHSKSEFSTN EPVISVVLQL AVIGQRIPNS NISLPRDWEA PLFFKVKSNQ QFRRVRIAYS ERKKVDNVVL VFQNQRLWDY GTPKGAGMLK VDTRLVVHAY CHSDFISLKR IKELEVEKLS SVTEDSTAQT CKLITLLLRS SKSEDLRLSI PVDFTVKDLI KRYCTEVKIS FHERIRLEFE GEWLDPNDQV QSTELEDEDQ VSVVLD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This has a subsequent role in the maintenance of chromosome structure. May work in conjunction with the Smc5-Smc6 complex.
  • 基因功能参考文献：
    1. These results suggest that Rhp51 and Rad60 are required for the restoration of a stalled or collapsed replication fork after release from the arrest of DNA replication [Rhb51][Rad60] PMID: 16354704
    2. role in protecting genome stability against spontaneous Top1-mediated DNA damage PMID: 21408210
    3. SUMO-like domains 1 of Rad60 is essential for viability, while SUMO-like domains 2 is not. PMID: 20885950
    4. results provide a mechanistic basis for the near-synonymous roles of Rad60 and SUMO in survival of genotoxic stress and suggest unprecedented DNA-damage-response functions for SLDs in regulating sumoylation PMID: 19363481
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: spo:SPBC1921.02

    STRING: 4896.SPBC1921.02.1