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  4. Recombinant Saccharomyces cerevisiae Small glutamine-rich tetratricopeptide repeat-containing protein 2 (SGT2)

Recombinant Saccharomyces cerevisiae Small glutamine-rich tetratricopeptide repeat-containing protein 2 (SGT2)

  • 中文名称：
    酿酒酵母SGT2重组蛋白
  • 货号：
    CSB-YP614180SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母SGT2重组蛋白
  • 货号：
    CSB-EP614180SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母SGT2重组蛋白
  • 货号：
    CSB-EP614180SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母SGT2重组蛋白
  • 货号：
    CSB-BP614180SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母SGT2重组蛋白
  • 货号：
    CSB-MP614180SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SGT2
  • Uniprot No.：
  • 别名：
    SGT2; YOR007C; UNF346; Small glutamine-rich tetratricopeptide repeat-containing protein 2; SGT/UBP; Viral protein U-binding protein
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-346
  • 氨基酸序列
    MSASKEEIAA LIVNYFSSIV EKKEISEDGA DSLNVAMDCI SEAFGFEREA VSGILGKSEF KGQHLADILN SASRVPESNK KDDAENVEIN IPEDDAETKA KAEDLKMQGN KAMANKDYEL AINKYTEAIK VLPTNAIYYA NRAAAHSSLK EYDQAVKDAE SAISIDPSYF RGYSRLGFAK YAQGKPEEAL EAYKKVLDIE GDNATEAMKR DYESAKKKVE QSLNLEKTVP EQSRDADVDA SQGASAGGLP DLGSLLGGGL GGLMNNPQLM QAAQKMMSNP GAMQNIQKMM QDPSIRQMAE GFASGGGTPN LSDLMNNPAL RNMAGNLFGG AGAQSTDETP DNENKQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2). Regulates Hsp70 ATPase activity. Required for recovery from heat shock.
  • 基因功能参考文献：
    1. Report demonstrated that Ybr137wp and the Sgt2 TPR domain interact directly. PMID: 25288638
    2. SGTA(Sgt2) associates with and specifically regulates the androgen, glucocorticoid, and progesterone receptors and has no effect on the mineralocorticoid and estrogen receptors in both yeast and mammalian cell-based reporter assays. PMID: 24753260
    3. The crystal structure of Sgt2 dimerization domain complexed with the Get5 Ubl domain (Sgt2N-Get5Ubl) is reported. PMID: 24100326
    4. Sgt2 increases the ability of excess Ssa to counteract [PSI(+)] curing by excess Hsp104. One region of Sgt2 interacts both with the prion domain of Sup35 and with tail-anchored proteins. PMID: 23045389
    5. S. cerevisiae sgt2Delta cells show partial defects in TA protein sorting. PMID: 21619481

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    SGT family
  • 数据库链接：

    KEGG: sce:YOR007C

    STRING: 4932.YOR007C