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  4. Recombinant Saccharomyces cerevisiae Non-disjunction protein 1 (NDJ1)

Recombinant Saccharomyces cerevisiae Non-disjunction protein 1 (NDJ1)

  • 中文名称：
    酿酒酵母NDJ1重组蛋白
  • 货号：
    CSB-YP618595SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母NDJ1重组蛋白
  • 货号：
    CSB-EP618595SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母NDJ1重组蛋白
  • 货号：
    CSB-EP618595SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母NDJ1重组蛋白
  • 货号：
    CSB-BP618595SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母NDJ1重组蛋白
  • 货号：
    CSB-MP618595SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NDJ1
  • Uniprot No.：
  • 别名：
    NDJ1; TAM1; YOL104C; Non-disjunction protein 1; Telomere-associated meiosis protein 1
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-352
  • 氨基酸序列
    MSKDNRLASI LLQPVASSSG NCTEFHDSKL HTLQEELNFL PLEGVASNVC PPMFRGHKNY VFVLYCLNQV DLVTNLQDST KRYYPLQIFK DCQLSSLVQK DFSHYFQLSR QKEGEDRNDS DTTLVNVVNS GVSRHRSQLL KMCIIPRICS FDKSNSKTYK LIQEYVNRFE TVLTKFGPEK DFTKVYANWS KLIESFNELI LHDLLVKWQQ WSELTQPNAT VHQNIPNVLR ELVIKLTQRY FTFQPSYSCS IDEFTTILLN KNALSLLDVF RKPRKYKLNF GLWLDCQNGI LIFTNGIVQM ADEITSERVK SFVRPAHLLV LEDHSNDEAV KKLMFFTFSA ILQCFTDEIL NC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for telomeric clustering (bouquet stage) during meiosis 1 prophase, formation and efficient homolog pairing, meiosis 1 disjunction, and telomere deletion during meiosis. Promotes also meiotic recombination.
  • 基因功能参考文献：
    1. we found a role for the meiotic bouquet in establishing the size dependence of centromere coupling, as abolishing bouquet (using the bouquet-defective spo11 ndj1 mutant) reduces it. Coupling in spo11 ndj1 rather follows telomere clustering preferences. We propose that a chromosome size preference for centromere coupling helps establish efficient homolog recognition. PMID: 27768699
    2. Ndj1p facilitates deletion (telomere-length shortening) by promoting telomeric interactions during meiosis, resulting in an effective increase in the concentration of limiting factors for deletion. PMID: 15694306
    3. Ndj1 promotes meiotic rcombination. PMID: 16648465
    4. Unlike Ndj1, Csm4 is not required for meiosis-specific telomere association. PMID: 18818741
  • 亚细胞定位：
    Nucleus. Chromosome, telomere.
  • 数据库链接：

    KEGG: sce:YOL104C

    STRING: 4932.YOL104C