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  4. Recombinant Saccharomyces cerevisiae Mitochondrial genome maintenance protein MGM101 (MGM101)

Recombinant Saccharomyces cerevisiae Mitochondrial genome maintenance protein MGM101 (MGM101)

  • 中文名称：
    酿酒酵母MGM101重组蛋白
  • 货号：
    CSB-YP329199SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母MGM101重组蛋白
  • 货号：
    CSB-EP329199SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母MGM101重组蛋白
  • 货号：
    CSB-EP329199SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母MGM101重组蛋白
  • 货号：
    CSB-BP329199SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母MGM101重组蛋白
  • 货号：
    CSB-MP329199SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MGM101
  • Uniprot No.：
  • 别名：
    MGM101; MGM9; YJR144W; J2181Mitochondrial genome maintenance protein MGM101
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    31-269
  • 氨基酸序列
    TATAGAVRKS FNSTETKPVF ATKSEAGNGS HMKEYSSGIN SKLGGTPLET RSTADDSLNN SYKQVKGDID WYTSWYGLGM KPFEAKVQKD LIEPLDPKDI EIKPDGLIYL PEIKYRRILN KAFGAGGWGL VPRSQTIVTS KLVTREYGLI CHGQLISVAR GEQDYFNEAG IPTATEGCKS NALMRCCKDL GVGSELWDPV FIKKFKVDHC TEKFVEHVTT KRKKKIWLRK DRQVEYPYK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Performs an essential function in the repair of oxidatively damaged mtDNA that is required for the maintenance of the mitochondrial genome. Binds to DNA.
  • 基因功能参考文献：
    1. The carboxy terminal-tail of Mgm101, likely displayed on the ring surface, is required for single stranded DNA binding. PMID: 23536705
    2. Data indicate that Mgm101p is found in the mitochondrial nucleoid along with enzymes and proteins involved in mtDNA replication. PMID: 23418572
    3. A potential role of Cys-216 and Cys-217 in regulating Mgm101 function and the repair of damaged mtDNA under stress conditions. PMID: 22948312
    4. Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination PMID: 22027892
    5. a previously identified recessive temperature-sensitive mgm101-1ts mutation was used as a detection system to examine the functionality of Mgm101p PMID: 17311591

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  • 亚细胞定位：
    Mitochondrion matrix, mitochondrion nucleoid.
  • 蛋白家族：
    MGM101 family
  • 数据库链接：

    KEGG: sce:YJR144W

    STRING: 4932.YJR144W