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  4. Recombinant Saccharomyces cerevisiae GTP-binding protein RHO5 (RHO5)

Recombinant Saccharomyces cerevisiae GTP-binding protein RHO5 (RHO5)

  • 中文名称：
    酿酒酵母RHO5重组蛋白
  • 货号：
    CSB-YP347442SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    酿酒酵母RHO5重组蛋白
  • 货号：
    CSB-EP347442SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    酿酒酵母RHO5重组蛋白
  • 货号：
    CSB-EP347442SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    酿酒酵母RHO5重组蛋白
  • 货号：
    CSB-BP347442SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    酿酒酵母RHO5重组蛋白
  • 货号：
    CSB-MP347442SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RHO5
  • Uniprot No.：
  • 别名：
    RHO5; YNL180C; N1644; GTP-binding protein RHO5
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-328
  • 氨基酸序列
    MRSIKCVIIG DGAVGKTSLL ISYTTNSFPT DYVPTVFDNY STTIAIPNGT ASSPLELDNG NDKRGSLSSA SSSPSTDRKL YKINLWDTAG QEDYDRLRPL CYPQTDIFLI CFSVSEHASF ANVTEKWLPE LKQTSNIEGT SLYTKLGKYP ILLVGTKSDL RDDPATQKKL QEANSDYVSQ EEIDELVQRC GFMGYTECSA ATQAGVREVF EQAVRYAIYE PESPNQKSAN HTLTDELTTA TTNTNGDKNI REQKQQPHHN NSTDSTLPKG SLQQEKEALN IKPTKKGQKD KIHEQSKSKG SKIASNNHHN KQAKPKTRND KKKKKSKC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Small GTPase that negatively regulates a MAP kinase branch, downstream of SLT2, of the PKC1-mediated signal transduction pathway. With its specific guanine nucleotide exchange factor (GEF), the heterodimeric complex DCK1/LMO1, relocates to mitochondria upon oxidative stress and triggers cell death. The DCK1/LMO1/RHO5 signaling module that mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy. The DCK1/LMO1/RHO5 signaling module plays also a function in cell wall integrity signaling.
  • 基因功能参考文献：
    1. Rho5 mediates H(2)O(2)-induced cell death by regulating the level of Trr1 or by excluding Trr1 from its cytoplasmic substrate. PMID: 18216266
  • 亚细胞定位：
    Membrane; Lipid-anchor. Mitochondrion.
  • 蛋白家族：
    Small GTPase superfamily, Rho family
  • 数据库链接：

    KEGG: sce:YNL180C

    STRING: 4932.YNL180C