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Recombinant Saccharomyces cerevisiae Chromosome stability protein 9 (CST9)

  • 中文名称:
    Recombinant Saccharomyces cerevisiae Chromosome stability protein 9(CST9),Yeast
  • 货号:
    CSB-YP312321SVG
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    Recombinant Saccharomyces cerevisiae Chromosome stability protein 9(CST9),Yeast
  • 货号:
    CSB-EP312321SVG
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    Recombinant Saccharomyces cerevisiae Chromosome stability protein 9(CST9),Yeast
  • 货号:
    CSB-EP312321SVG-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    Recombinant Saccharomyces cerevisiae Chromosome stability protein 9(CST9),Yeast
  • 货号:
    CSB-BP312321SVG
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    Recombinant Saccharomyces cerevisiae Chromosome stability protein 9(CST9),Yeast
  • 货号:
    CSB-MP312321SVG
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    CST9
  • Uniprot No.:
  • 别名:
    CST9; ZIP3; YLR394WChromosome stability protein 9; Molecular zipper protein 3
  • 种属:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度:
    full length protein
  • 表达区域:
    1-482
  • 氨基酸序列
    MGGYLAIVFI PQTNTKSMRE KKQKCLKQVR RLSLISPKKY IMPDSIFEQP FVYCGVCHRR TSHGDPLRLT SCAHILCSQH SPLTSKVCPI CRSSDISIIN LVESKQLPTD IRIFFEPLPP LLESLYNVSQ FQLNGLSKQC QYYQNHCLKL REKCARQQQL LYQAKIELDS MAILKKRIQE LESVLNHNNV SSMSVGVLPT RNSHQNHYQP PPTVDLTVDD NSLEEFEAKS FIKKLKKNSS LRNSSKNNNG TVTPSTSGRV NKNQPLFMET LNNPNRNSIP PPGMNPNANS NLPNISTIAE STNLNRFSFS PVRVAKGFDG KLPNLDILTN NGSVSSKNIS RLSSASLQPS SPLSSSSNRL ILPNSNLKEL HHSNTPLTST STQFPSALEK LKITRKRNNT ISGSNRITHN LSSHVRSSGL AFSSSSNSLQ QSKLPKSNIL KRSNSTQQLT NTHLKSDNHL PPRSSNTVLG SSKKNNKFRR IR
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Component of the synapsis initiation complex (SIC) necessary for the synaptonemal complex assembly. Stabilizes the ZIP2 component to the chromosomes. The SIC complex loads onto chromosomes and nucleates ZIP1 polymerization, a molecular zipper that acts to bring homologous chromosomes in close apposition, which is required for meiotic crossover. May also be involved in double strand break repair.
  • 基因功能参考文献:
    1. A tel1Delta mutant has globally increased amounts of Spo11-oligonucleotide complexes and altered Spo11-oligonucleotide lengths, consistent with conserved roles for Tel1 in control of DSB number and processing..We further find that effects of Tel1 are distinct but partially overlapping with previously described contributions of the recombination regulator Cst9 (also known as Zip3). PMID: 27923845
    2. proteolytic core and regulatory proteasome particles were recruited to chromosomes by Zip3, the ortholog of mammalian E3 ligase RNF212, and synaptonemal complex protein Zip1 . PMID: 28059715
    3. We show that Zip3 associates with DSB sites that are engaged in repair by CO, and Zip3 enrichment at DSBs reflects the DSB tendency to be repaired by CO. PMID: 23593021
    4. Spo22 (also called Zip4) is identified as a probable functional collaborator of Zip2/3 PMID: 16314568
  • 亚细胞定位:
    Nucleus. Chromosome. Note=Synapsed meiotic chromosomes.
  • 数据库链接:

    KEGG: sce:YLR394W

    STRING: 4932.YLR394W