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  4. Recombinant Reston ebolavirus Matrix protein VP40 (VP40)

Recombinant Reston ebolavirus Matrix protein VP40 (VP40)

  • 货号：
    CSB-YP810348RCJ
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP810348RCJ-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP810348RCJ
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP810348RCJ
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    VP40
  • Uniprot No.：
  • 别名：
    VP40Matrix protein VP40; Membrane-associated protein VP40
  • 种属：
    Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-331
  • 氨基酸序列
    MRRGVLPTAP PAYNDIAYPM SILPTRPSVI VNETKSDVLA VPGADVPSNS MRPVADDNID HSSHTPSGVA SAFILEATVN VISGTKVLMK QIPIWLPLGV ADQKIYSFDS TTAAIMLASY TVTHFGKISN PLVRVNRLGP GIPDHPLRLL RLGNQAFLQE FVLPPVQLPQ YFTFDLTALK LITQPLPAAT WTDETPAGAV NALRPGLSLH PKLRPILLPG KTGKKGHASD LTSPDKIQTI MNAIPDLKIV PIDPTKNIVG IEVPELLVQR LTGKKPQPKN GQPIIPVLLP KYVGLDPISP GDLTMVITQD CDSCHSPASH PYHMDKQNSY Q
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).
  • 基因功能参考文献：
    1. Hexameric model of VP40 using X-ray and electron microscopy was presented. PMID: 15908231
  • 亚细胞定位：
    Virion membrane; Peripheral membrane protein. Host late endosome membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein.
  • 蛋白家族：
    Filoviridae matrix protein VP40 family
  • 数据库链接：

    KEGG: vg:955192