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  4. Recombinant Rat THAP domain-containing protein 1 (Thap1)

Recombinant Rat THAP domain-containing protein 1 (Thap1)

  • 中文名称：
    大鼠Thap1重组蛋白
  • 货号：
    CSB-YP713153RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Thap1重组蛋白
  • 货号：
    CSB-EP713153RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Thap1重组蛋白
  • 货号：
    CSB-EP713153RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Thap1重组蛋白
  • 货号：
    CSB-BP713153RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Thap1重组蛋白
  • 货号：
    CSB-MP713153RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Thap1
  • Uniprot No.：
  • 别名：
    Thap1; THAP domain-containing protein 1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-210
  • 氨基酸序列
    MVQSCSAYGC KNRYDKDKPV SFHKFPLTRP SLCKQWEAAV RRKNFKPTKY SSICSEHFTP DCFKRECNNK LLKENAVPTI FLYIEPHEKK EELEPQEQLP SPSPPTSQVD AAVGLLMPPL QTPDNLSVFC DHNYTVEDTM HQRKRILHLE QQVEKLRKKL KTAQQRCRRQ ERQLEKLKEV VHFQREKDDA SERGYVILPN DYFEIVEVPA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
  • 基因功能参考文献：
    1. The prominent cytoplasmic and developmentally regulated expression of THAP1 suggests that THAP1 may function as part of a cell surface-nucleus signaling cascade involved in terminal neural differentiation. PMID: 23219941
  • 亚细胞定位：
    Nucleus, nucleoplasm. Nucleus, PML body.
  • 蛋白家族：
    THAP1 family
  • 数据库链接：

    KEGG: rno:306547

    STRING: 10116.ENSRNOP00000019026

    UniGene: Rn.52291