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  4. Recombinant Rat T-box transcription factor TBX5 (Tbx5)

Recombinant Rat T-box transcription factor TBX5 (Tbx5)

  • 中文名称：
    大鼠Tbx5重组蛋白
  • 货号：
    CSB-YP708407RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Tbx5重组蛋白
  • 货号：
    CSB-EP708407RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Tbx5重组蛋白
  • 货号：
    CSB-EP708407RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Tbx5重组蛋白
  • 货号：
    CSB-BP708407RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Tbx5重组蛋白
  • 货号：
    CSB-MP708407RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Tbx5T-box transcription factor TBX5; T-box protein 5
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-517
  • 氨基酸序列
    MADADEGFGL ARTPLEPDSK DRSCDSKPES ALGAPSKSPS SPQAAFTQQG MEGIKVFLHE RELWLKFHEV GTEMIITKAG RQMFPSYKVK VTGLNPKTKY ILLMDIVPAD DHRYKFADNK WSVTGKAEPA MPGRLYVHPD SPATGAHWMR QLVSFQKLKL TNNHLDPFGH IILNSMHKYQ PRLHIVKADE NNGFGSKNTA FCTHVFPETA FIAVTSYQNH KITQLKIENN PFAKGFRGSD DLELHRMSRM RSKEYPVVPR STVRHKVANH SPFSSETRAL STSSNLGSQY QCENGVSGPS QDLLPPPNPY PLAQEHSQIY HCTKRKDEEC SSTEHPYKKP YMETSPSEED TFYRSGYPQQ QGLSTSYRTE SAQRQACMYA SSAPPSEPVP SLEDISCNTW PSMPSYSSCT VTTVQPMDRL PYQHFSAHFT SGPLVPRLAG MANHGSPQLG EGMFQHQTSV THQPVVRQCG PQTGLQSPGS LQPPEFLYTH GVPRTLSPHQ YHSVHGVGMV PEWSENS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. Binds to the core DNA motif of NPPA promoter.
  • 基因功能参考文献：
    1. Tbx2, Tbx4 and Tbx5 are expressed throughout the mesenchyme of the developing lung, regulating the process of lung branching morphogenesis [12]. PMID: 27833996
    2. miR-10a may inhibit cardiac hypertrophy via targeting Tbx5. PMID: 28100873
    3. Findings provide a good basis for further identification of TBX5-related transcription factors and protein-protein interaction studies among each other. PMID: 16553207
    4. TBX5 and MEF2C physically associate through their DNA-binding domains to form a complex on the MYH6 promoter PMID: 19204083
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 数据库链接：

    KEGG: rno:304514

    STRING: 10116.ENSRNOP00000001893

    UniGene: Rn.6327