Recombinant Rat Selenoprotein P (Sepp1)
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中文名称:大鼠Selenop重组蛋白
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货号:CSB-YP021018RA
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规格:
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来源:Yeast
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其他:
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中文名称:大鼠Selenop重组蛋白
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货号:CSB-EP021018RA
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规格:
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来源:E.coli
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其他:
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中文名称:大鼠Selenop重组蛋白
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货号:CSB-EP021018RA-B
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规格:
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来源:E.coli
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共轭:Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他:
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中文名称:大鼠Selenop重组蛋白
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货号:CSB-BP021018RA
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规格:
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来源:Baculovirus
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其他:
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中文名称:大鼠Selenop重组蛋白
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货号:CSB-MP021018RA
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规格:
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来源:Mammalian cell
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其他:
产品详情
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纯度:>85% (SDS-PAGE)
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基因名:Selenop
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Uniprot No.:
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别名:Selenop; Selp; Sepp1; Selenoprotein P; SeP) [Cleaved into: Selenoprotein Se-P10; Selenoprotein Se-P6; Selenoprotein Se-P2; Selenoprotein Se-P1]
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种属:Rattus norvegicus (Rat)
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蛋白长度:Full Length of Mature Protein
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表达区域:20-385
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氨基酸序列E SQGQSPACKQ APPWNIGDQN PMLNSEGTVT VVALLQASUY LCLLQASRLE DLRIKLENQG YFNISYIVVN HQGSPSQLKH AHLKKQVSDH IAVYRQDEHQ TDVWTLLNGN KDDFLIYDRC GRLVYHLGLP YSFLTFPYVE EAIKIAYCEK RCGNCSFTSL EDEAFCKNVS SATASKTTEP SEEHNHHKHH DKHGHEHLGS SKPSENQQPG ALDVETSLPP SGLHHHHHHH KHKGQHRQGH LESUDMGASE GLQLSLAQRK LURRGCINQL LCKLSEESGA ATSSCCCHCR HLIFEKSGSA ITUQCAENLP SLCSUQGLFA EEKVIESCQC RSPPAAUHSQ HVSPTEASPN USUNNKTKKU KUNLN
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蛋白标签:Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
产品提供形式:Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
复溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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储存条件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
货期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事项:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet :Please contact us to get it.
相关产品
靶点详情
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功能:Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
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基因功能参考文献:
- A chromatin immunoprecipitation (ChIP) assay revealed that EPA decreases binding of SREBP-1c to the SELENOP promoter. Knockdown of Srebf1 resulted in a significant down-regulation of Selenop expression. PMID: 28465347
- Data indicate that Selenoprotein P SEPP1 processivity is intrinsic, but efficiency is governed by selenium levels. PMID: 25063811
- metformin decreases binding of FoxO3a, a direct target of AMPK, to the SEPP1 promoter. PMID: 24257750
- Sepp1 secreted from epithelial cells may support the intestinal immune system by providing immune cells (including plasma cells) with selenium PMID: 24157689
- apoER2-mediated uptake of long isoform Sepp1 is responsible for selenium distribution to tissues throughout the body. PMID: 22761431
- investigation of Sepp1 expression in adipocytes during adipogenesis and oxidative stress in models of obesity and insulin resistance PMID: 20959537
- tear SeP is a key molecule to protect the ocular surface cells against environmental oxidative stress PMID: 20360971
- mass spectrometric characterization of full-length protein and three isoforms shortened at the C terminus PMID: 11821412
- selenenylsulfide linkages Sec304-Cys314 and Cys306-Sec316 were present; selenoprotein P contains these two selenenylsulfide bonds PMID: 15712351
- Sertoli cell ApoER2 is a Sepp1 receptor and a component of the selenium delivery pathway to spermatogenic cells PMID: 17314095
- In conclusion, the selenoprotein P promoter is a target of the Akt/FoxO signal transduction cascade and SeP expression is regulated at the level of transcription by the forkhead box protein FoxO1a in human and rat hepatoma cells. PMID: 17986386
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亚细胞定位:Secreted.
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蛋白家族:Selenoprotein P family
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组织特异性:Widely expressed, mainly by the liver. Secreted in plasma.
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数据库链接:
KEGG: rno:29360
UniGene: Rn.1451
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