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  4. Recombinant Rat Sclerostin domain-containing protein 1 (Sostdc1)

Recombinant Rat Sclerostin domain-containing protein 1 (Sostdc1)

  • 中文名称：
    大鼠Sostdc1重组蛋白
  • 货号：
    CSB-EP734096RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Sostdc1重组蛋白
  • 货号：
    CSB-EP734096RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Name:Sostdc1 Synonyms:Usag1, Wise
  • Uniprot No.：
  • 别名：
    Sostdc1; Usag1; Wise; Sclerostin domain-containing protein 1; Uterine sensitization-associated gene 1 protein; USAG-1; Wnt-signaling modulator
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    24-206
  • 氨基酸序列
    FKNDATE ILYSHVVKPV SAHPSSNSTL NQARNGGRHF SSTGLDRNSR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE SVSPAKPAQH HRERKRASKS SKHSLS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling.
  • 基因功能参考文献：
    1. WISE contributes to renal dysfunction by promoting tubular atrophy and interstitial fibrosis. PMID: 23184054
    2. Rat homologue of the Xenopus-secreted WNT modulator Wise is expressed in the dermal papilla and not in the non-inductive dermal sheath and was additionally expressed at high levels in the precortex and in the putative bulge region [WISE]. PMID: 15373764
    3. we report the isolation, cloning, and characterization of a novel gene, uterine sensitization-associated gene-1 (UASG-1), that is preferentially expressed within the maximally sensitized/receptive rat endometrium PMID: 12390898
    4. Expression of Sostdc1 exhibits a ~10-fold increase at night in the rat pineal gland. PMID: 19103603
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Sclerostin family
  • 组织特异性：
    Highly expressed within the maximally sensitized/receptive endometrium. Weakly expressed in brain, kidney and the female reproductive tract. Expressed in the dermal papilla (DP) and at high level in the precortex of both anagen vibrissae and pelage follic
  • 数据库链接：

    KEGG: rno:266803

    STRING: 10116.ENSRNOP00000008106

    UniGene: Rn.2415