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  4. Recombinant Rat PDZ and LIM domain protein 1 (Pdlim1)

Recombinant Rat PDZ and LIM domain protein 1 (Pdlim1)

  • 中文名称：
    大鼠Pdlim1重组蛋白
  • 货号：
    CSB-YP017731RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Pdlim1重组蛋白
  • 货号：
    CSB-EP017731RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Pdlim1重组蛋白
  • 货号：
    CSB-EP017731RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Pdlim1重组蛋白
  • 货号：
    CSB-BP017731RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Pdlim1重组蛋白
  • 货号：
    CSB-MP017731RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pdlim1
  • Uniprot No.：
  • 别名：
    Pdlim1; Clim1; Clp36; PDZ and LIM domain protein 1; C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-327
  • 氨基酸序列
    TTQQIVLQG PGPWGFRLVG GKDFEQPLAI SRVTPGSKAA IANLCIGDLI TAIDGEDTSS MTHLEAQNKI KGCVDNMTLT VSRSEQKIWS PLVTEEGKRH PYKMNLASEP QEVLHIGSAH NRSAMPFTAS PAPGTRVITN QYNSPTGLYS SENISNFNNA VESKTSASGE EANSRPSAQP HPSGGLIIDK ESEVYKMLQE KQELNEPPKQ STSFLVLQEI LESDGKGDPN KPSGFRSVKA PVTKVAASVG NAQKLPICDK CGTGIVGVFV KLRDHHRHPE CYVCTDCGIN LKQKGHFFVG DQIYCEKHAR ERVTPPEGYD VVTVFPK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts.
  • 基因功能参考文献：
    1. The CLP36 has a redundant role in the formation of stress fibers, but have different effects on stress fiber dynamics in F2408 cells. PMID: 22659164
    2. expression linked to the differentiation of Rcho-1 cells PMID: 20599268
    3. CLP36 may interact with palladin to influence neurite outgrowth during sciatic nerve regeneration. PMID: 20381583
    4. These findings indicate that CLP36 plays a critical role in stress fiber formation and the assembly of focal adhesions in BeWo cells. PMID: 17964547
    5. This study suggested that CLP36 serves as a scaffold to form a multiprotein complex that regulates actin cytoskeleton dynamics and plays a role in controlling neurite outgrowth. PMID: 19780892

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  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
  • 组织特异性：
    Expressed most abundantly in heart, lung and liver, moderately in spleen and skeletal muscle, and at extremely low levels (if at all) in testis and brain tissues.
  • 数据库链接：

    KEGG: rno:54133

    STRING: 10116.ENSRNOP00000022000

    UniGene: Rn.11170