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  4. Recombinant Rat P2X purinoceptor 6 (P2rx6), partial

Recombinant Rat P2X purinoceptor 6 (P2rx6), partial

  • 中文名称：
    大鼠P2rx6重组蛋白
  • 货号：
    CSB-YP017324RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠P2rx6重组蛋白
  • 货号：
    CSB-EP017324RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠P2rx6重组蛋白
  • 货号：
    CSB-EP017324RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠P2rx6重组蛋白
  • 货号：
    CSB-BP017324RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠P2rx6重组蛋白
  • 货号：
    CSB-MP017324RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    P2rx6; P2rxl1P2X purinoceptor 6; P2X6; ATP receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor for ATP that acts as a ligand-gated ion channel.
  • 基因功能参考文献：
    1. P2X4 and P2X6 proteins were expressed in a different way during rat small intestine development, showing a higher colocalization coefficient at age P30 in both intestine regions. Those results suggest that purinergic receptors may play a role in intestinal maturation, which is associated with age and intestinal region. PMID: 27545450
    2. The study explores the association of the phenotype of ATP-activated current with the genotype of P2X1-6 subunits in neurons innervating tooth-pulp. PMID: 25680470
    3. P2X(4) and P2X(6) purinoreceptors are present in the gut from birth and that they are differentially distributed among regions PMID: 22230887
    4. The P2X6 receptor subunit is widely expressed in neuropils in the whole gray matter except for the dorsal superficial layer of the dorsal horn. PMID: 21669492
    5. Results suggest a direct relationship between purinergic P2X2/6 receptor expression and induction of neuronal differentiation in mitogen-free cultured rat neurospheres. PMID: 20617399
    6. The P2X(6) receptors are mainly expressed on intrinsic sensory neurons and that ATP, via P2X(6) receptors probably in heteromeric combination with P2X(2) receptors, may be involved in regulating the physiological functions of these neurons. PMID: 19946698
    7. P2X(2) receptors are trimers, whereas the P2X(6) receptor subunits do not form stable oligomers PMID: 15657042

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    P2X receptor family
  • 数据库链接：

    KEGG: rno:25041

    STRING: 10116.ENSRNOP00000002558

    UniGene: Rn.10258