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Recombinant Rat Neuronal pentraxin-1 (Nptx1)

  • 中文名称：
    大鼠Nptx1重组蛋白
  • 货号：
    CSB-YP016029RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Nptx1重组蛋白
  • 货号：
    CSB-EP016029RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Nptx1重组蛋白
  • 货号：
    CSB-EP016029RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Nptx1重组蛋白
  • 货号：
    CSB-BP016029RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Nptx1重组蛋白
  • 货号：
    CSB-MP016029RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Nptx1; Neuronal pentraxin-1; NP1; 47 kDa taipoxin-binding protein; Neuronal pentraxin I; NP-I
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    23-432
  • 氨基酸序列
    QDFGPTRF ICTSVPVDAD MCAASVAAGG AEELRSNVLQ LRETVLQQKE TILSQKETIR ELTTKLGRCE SQSTLDAGPG EARSGGGRKQ PGSGKNTMGD LSRTPASETL SQLGQTLQSL KTRLENLEQY SRLNSSSQTN SLKDLLQSKI DDLERQVLSR VNTLEEGKGG PKNDTEERAK IESALTSLHQ RISELEKGQK DNRPGDKFQL TFPLRTNYMY AKVKKSLPEM YAFTVCMWLK SSAAPGVGTP FSYAVPGQAN ELVLIEWGNN PMEILINDKV AKLPFVINDG KWHHICVTWT TRDGVWEAYQ DGTQGGNGEN LAPYHPIKPQ GVLVLGQEQD TLGGGFDATQ AFVGELAHFN IWDRKLTPGE VYNLATCSSK ALSGNVIAWA ESQIEIFGGA TKWTFEACRQ IN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
  • 基因功能参考文献：
    1. Rescue of NP1 expression in the rostral ventromedial medulla (RVM) restores behavioral hypersensitivity of knock-out mice, demonstrating a key role of NP1 in the pathogenesis of neuropathic pain. PMID: 22956834
    2. Our results show that neuronal pentraxin 1 induction mediates hypoxic-ischemic injury probably by interacting with and modulating GluR1 and potentially other excitatory glutamate receptors PMID: 15115814
  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle.
  • 组织特异性：
    Cerebellum, hippocampus and cerebral cortex.
  • 数据库链接：

    KEGG: rno:266777

    STRING: 10116.ENSRNOP00000005067

    UniGene: Rn.54707