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Recombinant Rat Neurogenin-1 (Neurog1)

  • 中文名称：
    大鼠Neurog1重组蛋白
  • 货号：
    CSB-YP015730RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Neurog1重组蛋白
  • 货号：
    CSB-EP015730RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Neurog1重组蛋白
  • 货号：
    CSB-EP015730RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Neurog1重组蛋白
  • 货号：
    CSB-BP015730RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Neurog1重组蛋白
  • 货号：
    CSB-MP015730RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Neurog1; Neurod3; Ngn; Ngn1Neurogenin-1; NGN-1; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-244
  • 氨基酸序列
    MPAPLETCLS DLDCASSNSG SDLSSFLTDE EDCARLQPLA STSGLSVPAR RSAPTLSGAS NVPGGQDEEQ ERRRRRGRAR VRSEALLHSL RRSRRVKAND RERNRMHNLN AALDALRSVL PSFPDDTKLT KIETLRFAYN YIWALAETLR LADQGLPGGG ARERLLPPQC VPCLPGPPSP ASDTESWGSG AAASPCATVA SPLSDPSSPS ASEDFTYGPG GPLFSFPGLP KDLLHTTPCF IPYH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis.
  • 基因功能参考文献：
    1. Tumor necrosis factor-alpha converting enzyme (TACE) may play a role in modulating repulsive guidance molecule (RGM)-induced repulsive behavior of neurons by regulating neogenin expression on the cell surface. PMID: 21645559
    2. Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells. PMID: 11923194
    3. Ngn1 is required for Akt-mediated neuronal differentiation and neurite outgrowth PMID: 16136056
    4. Results identify ERK5 phosphorylation of Neurogenin 1 as a novel mechanism regulating neuronal fate commitment of cortical progenitors. PMID: 19365559
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expression restricted to the embryonic nervous system.
  • 数据库链接：

    KEGG: rno:29410

    STRING: 10116.ENSRNOP00000015916

    UniGene: Rn.10606