Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Rat Growth factor receptor-bound protein 7 (Grb7)

Recombinant Rat Growth factor receptor-bound protein 7 (Grb7)

  • 中文名称：
    大鼠Grb7重组蛋白
  • 货号：
    CSB-YP009890RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Grb7重组蛋白
  • 货号：
    CSB-EP009890RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Grb7重组蛋白
  • 货号：
    CSB-EP009890RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Grb7重组蛋白
  • 货号：
    CSB-BP009890RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Grb7重组蛋白
  • 货号：
    CSB-MP009890RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Grb7
  • Uniprot No.：
  • 别名：
    Grb7Growth factor receptor-bound protein 7; Epidermal growth factor receptor GRB-7; GRB7 adapter protein
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-535
  • 氨基酸序列
    MELDLSPSHL SSSPEDVCPT PGTPPETPPP PDNPPPGDVK RSQPLPIPSS RKLREEEFQA TSLPSIPNPF PELCSPPSQK PILGGSSGAR GLLPRDSSRL CVVKVYSEDG ACRSVEVAAG ATARHVCEML VQRAHALSDE NWGLVECHPY LALERGLEDH ESVVEVQEAW PVGGDSRFIF RKNFAKYELF KSPPHTLFPE KMVSSCLDTP TGISHEDLIQ NFLNAGSFPE IQGFLQLRGS GRGSGRKLWK RFFCFLRRSG LYYSTKGTSK DPRHLQYVAD INESNVYVVT QGRKLYGIPT DFGFCVKPNK LRNGHKGLHI FCSEDEQSRT CWLSAFRLFK YGVQLYKNYQ QAQSRHLRLS YLGSPPLRSV SDNTLVAMDF SGHAGRVIEN PQEALSAATE EAQAWRKKTN HRLSLPTPCS GLSLSAAIHR TQPWFHGRIS REESQRLIGQ QGLVDGVFLV RESQRNPQGF VLSLCHLQKV KHYLILPSED EGCLYFSMDD GQTRFTDLLQ LVEFHQLNRG ILPCLLRHCC ARVAL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.
  • 亚细胞定位：
    Cytoplasm. Cell projection. Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic granule.
  • 蛋白家族：
    GRB7/10/14 family
  • 组织特异性：
    Detected in liver, kidney and placenta, and at lower levels in lung.
  • 数据库链接：

    KEGG: rno:84427

    STRING: 10116.ENSRNOP00000009299

    UniGene: Rn.28109