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  4. Recombinant Rat Doublecortin domain-containing protein 2 (Dcdc2)

Recombinant Rat Doublecortin domain-containing protein 2 (Dcdc2)

  • 中文名称：
    Recombinant Rat Doublecortin domain-containing protein 2(Dcdc2),Yeast
  • 货号：
    CSB-YP006539RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Doublecortin domain-containing protein 2(Dcdc2),Yeast
  • 货号：
    CSB-EP006539RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Doublecortin domain-containing protein 2(Dcdc2),Yeast
  • 货号：
    CSB-EP006539RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Doublecortin domain-containing protein 2(Dcdc2),Yeast
  • 货号：
    CSB-BP006539RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Doublecortin domain-containing protein 2(Dcdc2),Yeast
  • 货号：
    CSB-MP006539RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Dcdc2
  • Uniprot No.：
  • 别名：
    Dcdc2Doublecortin domain-containing protein 2
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-475
  • 氨基酸序列
    MNGPSPRSSH LSQPVVKSVL VYRNGDPFFA GRRVVIHEKK VSSFDIFLKE VTGGVQAPFG AVRNIYTPRT GHRIRKLDQI ESGGNYVAGG QEAFKKLNYL DIGEIKKRPM EAVNTEVKPV IHSKINVSAR FRKALHEPCT IFLIANGDLI SPASRLLIPR KALNQWDHVL QMVTEKITLR SGAVHRLYTL EGKLVESGAE LENGQFYVAV GRDKFKRLPY SELLFDKSAM RRPYGQKASS LPPMVGSRKS KGSGNYRQSK STIGSSDNSS PQPLKRKGKK DSNSEKPTKV KQSVKSKNSH QAIPDNDEGI FKAGAERSET RGAAEVQEDE DTQVEVPVDQ RPAEIVDEEE DGEKTSKDAN QKDDFSAMNG EAEDRAGSKV ADAPEEEEGI PDQGEKKASP SRVNGGTDEE NGEELDQVTE ELQPTVDEKG KAEGDNSAQD EAGLDAQRPP RPEVTVTSPQ ENEGNESNKA SSAVA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Protein that plays a role in the inhibition of canonical Wnt signaling pathway. May be involved in neuronal migration during development of the cerebral neocortex. Involved in the control of ciliogenesis and ciliary length.
  • 基因功能参考文献：
    1. DCDC2 overexpression in C. elegans causes an abnormal neuronal phenotype that can only be seen in ciliated neurons. Together our results suggest a potential role for DCDC2 in the structure and function of primary cilia PMID: 21698230
    2. These results support the claim that knockdown of Dcdc2 expression results in neuronal migration disorders similar to those seen in the brains of dyslexics. PMID: 18313856
  • 亚细胞定位：
    Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, kinocilium. Cytoplasm, cytoskeleton.
  • 组织特异性：
    Expressed in hair cells of the inner ear.
  • 数据库链接：

    KEGG: rno:291130

    STRING: 10116.ENSRNOP00000060289

    UniGene: Rn.45430