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  4. Recombinant Rat Cell surface glycoprotein CD200 receptor 1 (Cd200r1), partial

Recombinant Rat Cell surface glycoprotein CD200 receptor 1 (Cd200r1), partial

  • 中文名称：
    Recombinant Rat Cell surface glycoprotein CD200 receptor 1(Cd200r1),partial,Yeast
  • 货号：
    CSB-YP866839RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Rat Cell surface glycoprotein CD200 receptor 1(Cd200r1),partial,Yeast
  • 货号：
    CSB-EP866839RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Rat Cell surface glycoprotein CD200 receptor 1(Cd200r1),partial,Yeast
  • 货号：
    CSB-EP866839RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Rat Cell surface glycoprotein CD200 receptor 1(Cd200r1),partial,Yeast
  • 货号：
    CSB-BP866839RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Rat Cell surface glycoprotein CD200 receptor 1(Cd200r1),partial,Yeast
  • 货号：
    CSB-MP866839RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Cd200r1; Mox2r; Ox2r; Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; OX102 antigen
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli.
  • 基因功能参考文献：
    1. CD200R in the rat is mainly expressed on myeloid cells but also on non-myeloid cell subsets, and rat cytomegalovirus e127 can deliver inhibitory signals to immune cells by engaging CD200R. PMID: 30032349
    2. In the context of an acute response, CD200 potently interferes with local immunopathogenic mechanisms, most likely through the activation of CD200R. PMID: 25569356
    3. Results suggest that dysfunction of CD200-CD200R signalling may be involved in the aetiopathogenesis of Parkinson disease. PMID: 22053982
    4. We show that the rat cytomegalovirus CD200 orthologue (e127) binds CD200R on rat peritoneal macrophages. PMID: 21471232
    5. The CD200-CD200R pathway seems of critical relevance for macrophage-mediated damage in autoimmune inflammation of the CNS. PMID: 18164423

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD200R family
  • 组织特异性：
    Restricted to cells of the myeloid lineage.
  • 数据库链接：

    KEGG: rno:64357

    STRING: 10116.ENSRNOP00000002799

    UniGene: Rn.124439