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  4. Recombinant Rabbit Tripartite motif-containing protein 72 (TRIM72)

Recombinant Rabbit Tripartite motif-containing protein 72 (TRIM72)

  • 中文名称：
    小圆锥花果TRIM72重组蛋白
  • 货号：
    CSB-YP636314RB
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小圆锥花果TRIM72重组蛋白
  • 货号：
    CSB-EP636314RB
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小圆锥花果TRIM72重组蛋白
  • 货号：
    CSB-EP636314RB-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小圆锥花果TRIM72重组蛋白
  • 货号：
    CSB-BP636314RB
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小圆锥花果TRIM72重组蛋白
  • 货号：
    CSB-MP636314RB
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TRIM72
  • Uniprot No.：
  • 别名：
    TRIM72; MG53; Tripartite motif-containing protein 72; Mitsugumin-53; Mg53
  • 种属：
    Oryctolagus cuniculus (Rabbit)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-477
  • 氨基酸序列
    MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCRACLSR VAGEPAADGT VNCPCCQAPT RPQALSTNLQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RVLVCGVCAS LGSHRGHRLL PAAEAHSRLK TQLPQQKLQL QEASMRKEKS VAVLEHQLTE VEETVRQFRG AVGEQLGKMR VFLAALEGSL DREAERVRSE AGVALRRELG GLHSYLEQLR QMEKVLEEVA DKPQTEFLMK YCLVTSRLQK ILAESPPPAR LDIQLPIISD DFKFQVWRKM FRALMPALEE LTFDPSSAHP SLVVSPTGRR VECSEQKAPP AGDDARQFDK AVAVVAQQLL SDGEHYWEVE VGDKPRWALG VMASEASRRG RLHAVPSQGL WLLGLRDGKT LEAHVEAKEP RALRTPERRP TRLGLYLSFG DGVLAFYDAS DADALELLFA FRERLPGPVY PFFDVCWHDK GKNAQPLLLV GPDGQEA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
  • 亚细胞定位：
    Cell membrane, sarcolemma. Cytoplasmic vesicle membrane.
  • 蛋白家族：
    TRIM/RBCC family
  • 组织特异性：
    Muscle-specific.
  • 数据库链接：

    KEGG: ocu:100008639

    STRING: 9986.ENSOCUP00000019719

    UniGene: Ocu.5757