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Recombinant Polybia paulista Polybia-CP

  • 中文名称：
    Recombinant Polybia paulista Polybia-CP,Yeast
  • 货号：
    CSB-YP366254EXL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Polybia paulista Polybia-CP,Yeast
  • 货号：
    CSB-EP366254EXL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Polybia paulista Polybia-CP,Yeast
  • 货号：
    CSB-EP366254EXL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Polybia paulista Polybia-CP,Yeast
  • 货号：
    CSB-BP366254EXL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Polybia paulista Polybia-CP,Yeast
  • 货号：
    CSB-MP366254EXL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 别名：
    Polybia-CP; Polybia chemotactic peptide; Venom protein CP
  • 种属：
    Polybia paulista (Neotropical social wasp) (Swarm-founding polistine wasp)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    1-12
  • 氨基酸序列
    ILGTILGLLK SL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Potent antimicrobial peptide that is active against both Gram-positive and Gram-negative bacteria (B.subtilis (MIC=15 ug/ml or 4-16 uM), S.epidermidis (MIC=8-16 uM), S.aureus (MIC=15 ug/ml or 4 uM), E.coli (MIC=8-64 uM) and P.aeruginosa (MIC=64-128 uM)). Also shows cytotoxicity towards HEK293 cells (32 uM). Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane. Acts by disrupting bacterial membrane. Also acts in inflammation since it is chemotactic for polymorphonucleated leukocytes (PMNL). Shows potent antitumor activity against prostate and bladder cancer cell lines. Causes a reduced hemolysis to mammalian erythrocytes (HC(50)=50 uM) and has no mast cell degranulation activity at physiological concentrations. In addition, when tested in vitro on the parasite Trypanosoma cruzi (responsible of the Chagas disease), is able to reduce the number of the three forms (epimastigote, trypomastigote and amastigote), probably acting through the apoptotic cell death pathway.
  • 亚细胞定位：
    Secreted. Target cell membrane.
  • 蛋白家族：
    MCD family, Protonectin subfamily
  • 组织特异性：
    Expressed by the venom gland.