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  4. Recombinant Pig Plasminogen activator inhibitor 1 (SERPINE1)

Recombinant Pig Plasminogen activator inhibitor 1 (SERPINE1)

  • 中文名称：
    斯克罗法SERPINE1重组蛋白
  • 货号：
    CSB-YP021081PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法SERPINE1重组蛋白
  • 货号：
    CSB-EP021081PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法SERPINE1重组蛋白
  • 货号：
    CSB-EP021081PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法SERPINE1重组蛋白
  • 货号：
    CSB-BP021081PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法SERPINE1重组蛋白
  • 货号：
    CSB-MP021081PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    SERPINE1; PAI1; PLANH1; Plasminogen activator inhibitor 1; PAI; PAI-1; Endothelial plasminogen activator inhibitor; Serpin E1
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    24-402
  • 氨基酸序列
    SSHHQSL AARLATDFGV KVFRQVVQAS KDRNVVFSPY GVASVLAMLQ LTTAGDTQQQ IQEAMQFKIE EKGMAPALRQ LYKELMGPWN KDEISTADAI FVQRDLKLVQ GFMPYFFRLF RTTVKQVDFS EMDRARFIIN DWVKRHTKGM INDLLGQGAV DQLTRLVLVN ALYFNGQWKT PFPEKSTHHR LFHKSDGSTV SVPMMAQTNK FNYTEFSTPD GHYYDILELP YHGNTLSMFI AAPYEKEVPL SALTSILDAQ LISQWKGNMT RLTRLLVLPK FSLESEVDLR RPLENLGMTD MFRPNQADFS SLSDQELLYM SQALQKVKIE VNESGTVASS STAIIVSARM APEEIIMDRP FLFVVRHNPT GTVLFMGQVM EP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.
  • 基因功能参考文献：
    1. In one pig population and in female pigs, SERPINE1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1) was significantly associated with muscling, growth and fat accretion and in male animals with meat quality. PMID: 22497544
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Serpin family
  • 数据库链接：

    KEGG: ssc:396945

    UniGene: Ssc.9781