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  4. Recombinant Pig Inhibin alpha chain (INHA)

Recombinant Pig Inhibin alpha chain (INHA)

  • 中文名称：
    斯克罗法INHA重组蛋白
  • 货号：
    CSB-YP011718PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法INHA重组蛋白
  • 货号：
    CSB-EP011718PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法INHA重组蛋白
  • 货号：
    CSB-EP011718PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法INHA重组蛋白
  • 货号：
    CSB-BP011718PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法INHA重组蛋白
  • 货号：
    CSB-MP011718PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    INHA
  • Uniprot No.：
  • 别名：
    INHA; Inhibin alpha chain
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    231-364
  • 氨基酸序列
    STAPLPWPWS PAALRLLQRP PEEPAVHADC HRASLNISFQ ELGWDRWIVH PPSFIFHYCH GGCGLPTLPN LPLSVPGAPP TPVQPLLLVP GAQPCCAALP GTMRSLRVRT TSDGGYSFKY ETVPNLLTQH CACI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • 基因功能参考文献：
    1. Data suggest that, in granulosa cells, inhibin alpha-subunit is involved in regulation of cell proliferation, extracellular matrix remodeling, oogenesis, and ovulation. These studies were conducted in China and involved transcriptome sequencing analysis in cultured granulosa cells (from slaughterhouse pigs) exposed in vitro to a neutralizing anti-inhibin alpha-subunit antibody. PMID: 28082104
    2. The relationship of INHA insertion/deletion polymorphisms with follicular cysts was investigated PMID: 26521695
    3. This study provides evidence that the expressions of inhibin alpha subunit and betaglycan are inferior in cystic follicles, and this may be caused by the decrease in FSH in the presence of a cystic follicle. PMID: 26097017
    4. The c.-42G>A and c.3222G>A polymorphisms in the INHA gene are significantly associated with follicular cysts in sows. PMID: 26208435
    5. INHA and INHB expression and cellular localization in porcine oocytes were studied. PMID: 23226944
    6. Association of the INHA gene to ovulation rate. PMID: 16879365
    7. inhibin alpha-subunits were localized in the granulosa cells of follicles at all stages but were not localized in corpora lutea. PMID: 17132910

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 数据库链接：

    KEGG: ssc:397386

    STRING: 9823.ENSSSCP00000021670

    UniGene: Ssc.18993