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  4. Recombinant Paralyzed arrest at two-fold protein 6 (pat-6)

Recombinant Paralyzed arrest at two-fold protein 6 (pat-6)

  • 中文名称：
    秀丽隐杆线虫pat-6重组蛋白
  • 货号：
    CSB-YP522702CXY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    秀丽隐杆线虫pat-6重组蛋白
  • 货号：
    CSB-EP522702CXY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    秀丽隐杆线虫pat-6重组蛋白
  • 货号：
    CSB-EP522702CXY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    秀丽隐杆线虫pat-6重组蛋白
  • 货号：
    CSB-BP522702CXY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    秀丽隐杆线虫pat-6重组蛋白
  • 货号：
    CSB-MP522702CXY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    pat-6
  • Uniprot No.：
  • 别名：
    pat-6; T21D12.4; Paralyzed arrest at two-fold protein 6; Actopaxin homolog; Parvin-like protein
  • 种属：
    Caenorhabditis elegans
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-375
  • 氨基酸序列
    MSTLGRSKTP SRDEPKKPGV FEKLSGTLSR KKKAPEDEHG NQGGAHHATD EDEVLELELE GREALDQSLV PVLARNIWLE EGEIRRYLTK ETARDQKLAQ VVDLLIYWLN EELADQRIVV RHLQEDLFDG QIIQKLLEKL EQIRIEVPEV SQSEEGQRQK LQIVVQTANR ILGQPREQEK WSADLIHQKD FTAIIQLLVL LALHYRAPVR FPDNVVANVV VAQKEHGQVK THRITEQITT VQTELAPKGT RDAFDTLFDY GPDKLAHVKT SLLAFCNKHL NKINLEVSDL DNQFQDGVFL VLLVGLLEGY FVPLYHFNLQ VQSHEEKVKN VQFAFKLMED TGLEKPRSRV QDIANGDVKS TLRLLHLLFT KYKHI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the regulation of cell adhesion and cytoskeleton organization. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. During embryonic development, required to recruit cpna-1, unc-89 and myofilaments to newly forming integrin attachments composed of integrins pat-2/pat-3, pat-4 and unc-112. Also required to reposition the integrin-based attachments so that they form the highly ordered array of dense body and M-line attachments that are characteristic of mature muscle cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles.
  • 基因功能参考文献：
    1. PAT-6/actopaxin plays essential roles during the maturation of integrin-mediated muscle attachments in vivo. PMID: 12781130
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, M line. Perikaryon. Cell projection, axon.
  • 蛋白家族：
    Parvin family
  • 组织特异性：
    Expressed from 1.5 stage embryos, mostly within the muscle cells. In adult hermaphrodites, expressed in the attachments of other muscles, including the uterine, anal depressor, anal sphincter, and vulval muscles, as well as in the spermatheca and the dist
  • 数据库链接：

    KEGG: cel:CELE_T21D12.4

    STRING: 6239.T21D12.4.2

    UniGene: Cel.12540